HitPredict

Interactor 1: KEAP1 (Q14145)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)
Gene: KEAP1

Interactor 2: KLH24 (Q6TFL4)
Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1)
Gene: KLHL24

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.27 1.00 0.527

The method score is based on:

Property Details
Experiments 35044719
Identification Methods unspecified method
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BACK~Kelch_1, BTB~BTB, Kelch_1~Kelch_1
Common GO terms GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 624
Hs

1 600
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Service provided by Combinatics, Japan

Last updated: 11Aug2025