HitPredict

Interactor 1: IGSF3 (O75054)
Immunoglobulin superfamily member 3 (IgSF3) (Glu-Trp-Ile EWI motif-containing protein 3) (EWI-3)
Gene: IGSF3

Interactor 2: CD9 (P21926)
CD9 antigen (5H9 antigen) (Cell growth-inhibiting gene 2 protein) (Leukocyte antigen MIC3) (Motility-related protein) (MRP-1) (Tetraspanin-29) (Tspan-29) (p24) (CD antigen CD9)
Gene: CD9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	26686862
Identification Methods	anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1194 Hs			1 228
+	Hs
		253639 IGSF3_HUMAN (1-1194): 0: 758: 100.00		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		253665 IGSF3_HUMAN (1-1194): 0: 758: 100.00		TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02
+	Hs
		602274 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		905541 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		887922 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Mm
		728559 IGSF8_MOUSE (689-1117): 4.78e-34: 141: 18.91		CD81_MOUSE (1-225): 2.11e-51: 168: 44.87
+	Hs
		602263 SDK2_HUMAN (583-1172): 1.81e-22: 107: 12.14		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		653096 IGSF8_HUMAN (689-1117): 1.79e-34: 143: 17.31		CD82_HUMAN (4-224): 3.81e-46: 155: 24.23
+	Hs
		602297 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		905517 SDK2_HUMAN (583-1172): 1.81e-22: 107: 12.14		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		888000 ROBO1_HUMAN (7-547): 2.78e-18: 93.5: 12.35		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		602290 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		CD9_HUMAN (1-228): 5.13e-61: 192: 100.00
+	Hs
		905572 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		TSN5_HUMAN (7-225): 1.94e-53: 174: 23.64
+	Hs
		887973 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		CD81_HUMAN (1-225): 2.3e-53: 173: 43.59
+	Hs
		446077 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		CD63_HUMAN (1-228): 1.71e-52: 170: 24.49
+	Hs
		819474 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		CD151_HUMAN (3-222): 5.02e-51: 167: 30.08
+	Hs
		1245273 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		TSN14_HUMAN (11-225): 6.56e-49: 162: 24.02
+	Hs
		1199563 TITIN_HUMAN (8-138): 9.96e-10: 65.7: 13.24		TSN33_HUMAN (10-224): 1.17e-48: 162: 20.08
+	Hs
		653105 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		CD82_HUMAN (4-224): 3.81e-46: 155: 24.23
+	Hs
		237768 FPRP_HUMAN (830-1141): 2.36e-10: 67.3: 15.84		TSN2_HUMAN (3-228): 1.77e-44: 150: 46.46