HitPredict

Interactor 1: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 529 Hs			1 768
+	Hs
		142546 IMA3_HUMAN (4-529): 4.71e-150: 441: 50.10		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		138684 IMA4_HUMAN (4-529): 2.57e-146: 432: 49.25		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		253625 IMA7_HUMAN (1-528): 2.65e-140: 417: 45.37		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		179044 IMA6_HUMAN (1-528): 6.67e-136: 406: 45.02		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		911238 IMA5_HUMAN (4-528): 4.81e-131: 393: 43.91		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		910889 IMA1_HUMAN (1-529): 6.81e-163: 474: 100.00		CUL4B_HUMAN (5-768): 0: 796: 36.77
+	Hs
		142547 IMA3_HUMAN (4-529): 4.71e-150: 441: 50.10		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	Hs
		142548 IMA3_HUMAN (4-529): 4.71e-150: 441: 50.10		CUL4B_HUMAN (5-768): 0: 796: 36.77
+	Hs
		138685 IMA4_HUMAN (4-529): 2.57e-146: 432: 49.25		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	Hs
		911239 IMA5_HUMAN (4-528): 4.81e-131: 393: 43.91		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	Hs
		911240 IMA5_HUMAN (4-528): 4.81e-131: 393: 43.91		CUL4B_HUMAN (5-768): 0: 796: 36.77
+	Hs
		910887 IMA1_HUMAN (1-529): 6.81e-163: 474: 100.00		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		911237 IMA5_HUMAN (4-528): 4.81e-131: 393: 43.91		CUL1_HUMAN (18-768): 0: 709: 30.57