HitPredict

Interactor 1: FZD7 (O75084)
Frizzled-7 (Fz-7) (hFz7) (FzE3)
Gene: FZD7

Interactor 2: AT2B2 (Q01814)
Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)
Gene: ATP2B2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0030165 - PDZ domain binding GO:0030182 - neuron differentiation GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 574 Hs			1 1243
+	Hs
		966806 FZD2_HUMAN (34-574): 0: 743: 79.93		AT2B2_HUMAN (1-1243): 0: 1285: 100.00
+	Hs
		254151 FZD7_HUMAN (1-574): 0: 795: 100.00		AT2B1_HUMAN (1-1243): 0: 1186: 78.86
+	Hs
		966899 FZD10_HUMAN (16-561): 0: 686: 46.35		AT2B2_HUMAN (1-1243): 0: 1285: 100.00
+	Hs
		254154 FZD7_HUMAN (1-574): 0: 795: 100.00		AT2B4_HUMAN (1-1243): 0: 1154: 68.56