HitPredict

Interactor 1: DEPD5 (O75140)
GATOR1 complex protein DEPDC5 (DEP domain-containing protein 5)
Gene: DEPDC5

Interactor 2: NPRL3 (Q12980)
GATOR1 complex protein NPRL3 (-14 gene protein) (Alpha-globin regulatory element-containing gene protein) (Nitrogen permease regulator 3-like protein) (Protein CGTHBA)
Gene: NPRL3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.735

The method score is based on:

Property	Details
Experiments	23723238, 28199306, 25263562, 28199315, 33961781, 25366275
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005096 - GTPase activator activity GO:0005765 - lysosomal membrane GO:0010508 - positive regulation of autophagy GO:0032007 - negative regulation of TOR signaling GO:0034198 - cellular response to amino acid starvation and 2 others more... GO:1904262 - negative regulation of TORC1 signaling GO:1990130 - GATOR1 complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	1603
Hs

1	569

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024