HitPredict

Interactor 1: OBSL1 (O75147)
Obscurin-like protein 1
Gene: OBSL1

Interactor 2: MACF1 (Q9UPN3)
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (620 kDa actin-binding protein) (ABP620) (Actin cross-linking family protein 7) (Macrophin-1) (Trabeculin-alpha)
Gene: MACF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	24711643, 31343991
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1896 Hs			1 7388
+	Hs
		234595 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		MACF1_HUMAN (1-7388): 0: 2387: 100.00
+	Mm
		250946 MYPC3_MOUSE (3-809): 1.8e-59: 228: 12.08		MACF1_MOUSE (1-7388): 0: 2164: 83.39
+	Hs
		255631 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		EPIPL_HUMAN (1538-2789): 1.49e-35: 154: 13.15
+	Hs
		255483 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		DESP_HUMAN (2737-3775): 9.21e-27: 124: 8.65
+	Hs
		255802 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Hs
		255932 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		255701 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		164539 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		SPTN2_HUMAN (3436-4815): 1.06e-11: 74.8: 9.59
+	Hs
		255580 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		UTRN_HUMAN (428-1437): 8.81e-11: 71.9: 13.98
+	Hs
		255470 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Hs
		255785 OBSL1_HUMAN (1-1896): 0: 1197: 100.00		GOGB1_HUMAN (6684-7219): 2.29e-10: 70.5: 9.23
+	Hs
		234520 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13
+	Mm
		250924 MYPC3_MOUSE (3-809): 1.8e-59: 228: 12.08		DMD_MOUSE (69-1516): 9.33e-77: 290: 18.75
+	Hs
		234551 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		SYNE1_HUMAN (343-1742): 3.05e-13: 80.2: 8.97
+	Hs
		234503 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		DYST_HUMAN (478-1511): 2.31e-12: 77.1: 9.72
+	Hs
		234502 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		SPTB2_HUMAN (6378-7134): 6.05e-11: 72.5: 13.80
+	Hs
		234468 DSCAM_HUMAN (235-1708): 9.72e-118: 417: 12.43		ACTN1_HUMAN (921-1398): 1.47e-10: 70.5: 9.07
+	Mm
		250941 MYPC3_MOUSE (3-809): 1.8e-59: 228: 12.08		Q91ZE6_MOUSE (5920-6817): 1.13e-11: 74.7: 22.28
+	Mm
		93253 MYPC3_MOUSE (3-809): 1.8e-59: 228: 12.08		E9PX29_MOUSE (5920-6817): 1.13e-11: 74.7: 22.28
+	Hs
		1068678 MXRA5_HUMAN (1-97): 5.61e-10: 67: 17.35		PLEC_HUMAN (2677-3656): 8.53e-27: 124: 8.13