HitPredict

Interactor 1: KDM4A (O75164)
Lysine-specific demethylase 4A (EC 1.14.11.66) (EC 1.14.11.69) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) ([histone H3]-trimethyl-L-lysine(36) demethylase 4A) ([histone H3]-trimethyl-L-lysine(9) demethylase 4A)
Gene: KDM4A

Interactor 2: MCM3 (P25205)
DNA replication licensing factor MCM3 (EC 3.6.4.12) (DNA polymerase alpha holoenzyme-associated protein P1) (P1-MCM3) (RLF subunit beta) (p102)
Gene: MCM3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.39	0.60	0.484

Property	Details
Experiments	23871696
Identification Methods	pull down, anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1064 Hs			1 808
+	Hs
		256954 KDM4A_HUMAN (1-1064): 0: 1133: 100.00		MCM2_HUMAN (10-721): 0: 707: 30.62
+	Hs
		256946 KDM4A_HUMAN (1-1064): 0: 1133: 100.00		MCM5_HUMAN (9-713): 0: 685: 28.92
+	Hs
		256945 KDM4A_HUMAN (1-1064): 0: 1133: 100.00		MCM4_HUMAN (9-739): 0: 661: 28.03
+	Hs
		256947 KDM4A_HUMAN (1-1064): 0: 1133: 100.00		MCM7_HUMAN (10-669): 0: 650: 31.62
+	Sc
		667628 GIS1_YEAST (4-312): 1.59e-87: 303: 27.94		MCM2_YEAST (6-668): 0: 664: 32.15
+	Dm
		1359684 KDM5_DROME (3-60): 3.08e-14: 80: 36.21		MCM6_DROME (3-800): 0: 686: 25.89
+	Dm
		1099476 KDM5_DROME (3-60): 3.08e-14: 80: 36.21		MCM4_DROME (28-664): 0: 649: 30.51
+	Sc
		667886 GIS1_YEAST (4-312): 1.59e-87: 303: 27.94		MCM5_YEAST (8-650): 1.72e-86: 292: 31.51