HitPredict

Interactor 1: PP6R2 (O75170)
Serine/threonine-protein phosphatase 6 regulatory subunit 2 (SAPS domain family member 2)
Gene: PPP6R2

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.681

Property	Details
Experiments	20065038, 28514442, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 966 Hs			1 4128
+	Hs
		944277 PP6R3_HUMAN (1-914): 0: 746: 46.31		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		944480 PP6R1_HUMAN (1-898): 0: 640: 39.94		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Sc
		715201 SA185_YEAST (365-717): 5.56e-41: 165: 14.25		TOR1_YEAST (2759-4127): 0: 677: 15.92
+	Sc
		715218 SAP4_YEAST (364-604): 6.85e-40: 161: 16.18		TOR1_YEAST (2759-4127): 0: 677: 15.92
+	Hs
		1031555 HUWE1_HUMAN (487-954): 7.07e-26: 118: 13.22		ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42
+	Hs
		554305 MUC1_HUMAN (714-965): 9.55e-20: 97.4: 17.54		ATM_HUMAN (3218-4128): 1.84e-158: 557: 19.42
+	Sc
		755423 SA185_YEAST (365-717): 5.56e-41: 165: 14.25		TRA1_YEAST (2924-4127): 1.79e-115: 416: 14.57