HitPredict

Interactor 1: TRI13 (O60858)
E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13)
Gene: TRIM13

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 407 Hs			1 1620
+	Hs
		258224 TRI13_HUMAN (1-407): 1.13e-132: 388: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		258225 TRI13_HUMAN (1-407): 1.13e-132: 388: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		710888 TRI54_HUMAN (1-294): 1.04e-53: 183: 20.32		EPHB2_HUMAN (938-1436): 1.28e-127: 427: 23.26
+	Hs
		258227 TRI13_HUMAN (1-407): 1.13e-132: 388: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		439761 TRI72_HUMAN (3-291): 1.97e-57: 196: 22.67		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		650490 TRI35_HUMAN (2-316): 3.12e-54: 188: 16.87		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Mm
		581960 TRI72_MOUSE (4-322): 1.32e-52: 184: 18.77		INSR_MOUSE (973-1484): 6.99e-113: 392: 32.38
+	Mm
		584834 TR30A_MOUSE (1-301): 1.44e-54: 190: 19.48		NTRK1_MOUSE (1111-1390): 1.49e-63: 235: 42.71