Interactor 1: GLRA3 (O75311)
Glycine receptor subunit alpha-3
Gene: GLRA3

Interactor 2: GLRB (P48167)
Glycine receptor subunit beta (Glycine receptor 58 kDa subunit)
Gene: GLRB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Neur_chan_LBD~Neur_chan_LBD, Neur_chan_LBD~Neur_chan_memb, Neur_chan_memb~Neur_chan_memb
Common GO terms GO:0004888 - transmembrane signaling receptor activity
GO:0005886 - plasma membrane
GO:0016594 - glycine binding
GO:0016934 - extracellularly glycine-gated chloride channel activity
GO:0016935 - glycine-gated chloride channel complex
and 8 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 464
Hs

1 497
+ Hs
+ Hs
+ Hs
+ Hs
+ Dr
+ Mm
+ Mm
+ Mm
+ Hs
+ Rn
+ Mm
+ Rn
+ Mm
+ Mm
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+ Mm
+ Mm

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Last updated: 15 Jul 2024