HitPredict

Interactor 1: UBP12 (O75317)
Ubiquitin carboxyl-terminal hydrolase 12 (EC 3.4.19.12) (Deubiquitinating enzyme 12) (Ubiquitin thioesterase 12) (Ubiquitin-hydrolyzing enzyme 1) (Ubiquitin-specific-processing protease 12)
Gene: USP12

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19075014
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 370 Hs			1 685
+	Hs
		475566 UBP46_HUMAN (5-370): 2.53e-133: 387: 88.53		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476400 UBP42_HUMAN (16-368): 4.56e-100: 324: 24.79		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475440 UBP8_HUMAN (2-367): 6.3e-101: 323: 27.44		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476493 UBP36_HUMAN (15-368): 1.35e-98: 317: 24.65		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		271022 UBP2_HUMAN (17-367): 2.39e-102: 316: 25.68		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476545 UBP21_HUMAN (10-367): 2.35e-101: 312: 24.30		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		475932 U17L2_HUMAN (5-369): 6.28e-101: 310: 23.91		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476579 UBP22_HUMAN (7-369): 7.91e-100: 306: 24.94		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		64200 UBP27_HUMAN (7-369): 3.25e-100: 305: 23.28		UBC_HUMAN (1-685): 0: 846: 100.00
+	At
		1210479 UBP15_ARATH (38-368): 4.17e-93: 299: 27.00		UBQ10_ARATH (305-685): 2.63e-153: 453: 95.80
+	At
		1092065 UBP15_ARATH (38-368): 4.17e-93: 299: 27.00		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1091741 UBP13_ARATH (35-368): 1.39e-91: 298: 27.10		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Mm
		477008 UBP12_MOUSE (1-370): 1.23e-140: 405: 98.38		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Mm
		476741 UBP46_MOUSE (5-370): 2.53e-133: 387: 88.53		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		474982 UBP46_HUMAN (5-370): 2.53e-133: 387: 88.53		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		924201 UBP36_HUMAN (15-368): 1.35e-98: 317: 24.65		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		476865 UBP8_MOUSE (5-367): 2.18e-100: 321: 27.20		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Rn
		1137288 UBP2_RAT (27-367): 3.05e-102: 316: 26.39		UBC_RAT (1-108): 1.27e-29: 127: 90.74
+	Hs
		398134 UBP21_HUMAN (10-367): 2.35e-101: 312: 24.30		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	Hs
		271114 UBP2_HUMAN (17-367): 2.39e-102: 316: 25.68		Q5U5U6_HUMAN (1-77): 7.83e-26: 108: 98.70