HitPredict

Interactor 1: BRD4 (O60885)
Bromodomain-containing protein 4 (Protein HUNK1)
Gene: BRD4

Interactor 2: CDC27 (P30260)
Cell division cycle protein 27 homolog (Anaphase-promoting complex subunit 3) (APC3) (CDC27 homolog) (CDC27Hs) (H-NUC)
Gene: CDC27

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31239290, 30554943
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 1362 Hs			1 824
+	Hs
		718569 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		CDC27_HUMAN (1-824): 0: 630: 100.00
+	Hs
		674085 BRD2_HUMAN (3-737): 5.3e-54: 206: 46.43		CDC27_HUMAN (1-824): 0: 630: 100.00
+	Hs
		342118 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		CDC27_HUMAN (1-824): 0: 630: 100.00
+	Hs
		260589 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		APC7_HUMAN (290-823): 3.42e-61: 219: 16.28
+	Hs
		260095 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		CTR9_HUMAN (491-823): 2.86e-26: 118: 13.30
+	Hs
		260588 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		CDC23_HUMAN (371-823): 1.04e-24: 111: 12.64
+	Hs
		185286 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		OGT1_HUMAN (77-568): 9.79e-24: 109: 8.25
+	Hs
		259877 BRD4_HUMAN (1-1362): 1.08e-122: 416: 100.00		CDC16_HUMAN (437-823): 4.35e-14: 78: 10.80
+	Hs
		1141352 BRD3_HUMAN (37-737): 8.76e-57: 213: 47.73		APC7_HUMAN (290-823): 3.42e-61: 219: 16.28
+	Hs
		342359 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		APC7_HUMAN (290-823): 3.42e-61: 219: 16.28
+	Hs
		1446428 BRD7_HUMAN (238-731): 9.86e-30: 129: 10.56		APC7_HUMAN (290-823): 3.42e-61: 219: 16.28
+	Sc
		577576 GCN5_YEAST (140-462): 2.78e-42: 163: 14.41		CYC8_YEAST (533-823): 1.11e-42: 169: 16.17
+	Hs
		342358 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		CDC23_HUMAN (371-823): 1.04e-24: 111: 12.64
+	Hs
		342169 BRD1_HUMAN (192-769): 1.38e-30: 133: 13.50		CDC16_HUMAN (437-823): 4.35e-14: 78: 10.80