HitPredict

Interactor 1: SKAP2 (O75563)
Src kinase-associated phosphoprotein 2 (Pyk2/RAFTK-associated protein) (Retinoic acid-induced protein 70) (SKAP55 homolog) (SKAP-55HOM) (SKAP-HOM) (Src family-associated phosphoprotein 2) (Src kinase-associated phosphoprotein 55-related protein) (Src-associated adapter protein with PH and SH3 domains)
Gene: SKAP2

Interactor 2: TARA (Q9H2D6)
TRIO and F-actin-binding protein (Protein Tara) (TRF1-associated protein of 68 kDa) (Trio-associated repeat on actin)
Gene: TRIOBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PH, PH~SH3_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 359 Hs			1 2365
+	Hs
		1153376 PKHA7_HUMAN (26-316): 3.97e-42: 159: 14.52		TARA_HUMAN (1-2365): 4.78e-172: 589: 100.00
+	Hs
		1153259 PKHA7_HUMAN (26-316): 3.97e-42: 159: 14.52		MPRIP_HUMAN (1554-2357): 2.27e-56: 217: 33.82
+	Hs
		724876 PKHA7_HUMAN (26-316): 3.97e-42: 159: 14.52		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		254513 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		ROCK2_HUMAN (1806-2363): 5.22e-37: 156: 12.52
+	Hs
		551742 PKHA7_HUMAN (26-316): 3.97e-42: 159: 14.52		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		725019 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		MYH9_HUMAN (1312-2225): 5.12e-28: 126: 8.32
+	Hs
		725245 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		MYH10_HUMAN (1444-2225): 5.59e-28: 126: 9.89
+	Hs
		1068669 PKHA5_HUMAN (27-326): 3.7e-39: 150: 15.86		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		728515 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		MYH11_HUMAN (1483-2225): 1.16e-25: 119: 10.65
+	Hs
		1154076 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		NIPBL_HUMAN (297-1029): 2.39e-19: 98.5: 15.30
+	Hs
		965158 PKHA5_HUMAN (27-326): 3.7e-39: 150: 15.86		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82
+	Hs
		1068666 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		PLEC_HUMAN (1579-2357): 3.47e-16: 88.1: 12.43
+	Hs
		551837 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		DESP_HUMAN (1531-2365): 6.57e-16: 86.9: 10.21
+	Hs
		1056986 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		MDC1_HUMAN (88-903): 1.81e-15: 85.4: 14.49
+	Hs
		1189803 PKHA4_HUMAN (83-293): 2.34e-28: 118: 15.28		MYH14_HUMAN (2035-2363): 1.9e-15: 85.4: 15.06
+	Hs
		212310 CYH3_HUMAN (65-215): 8.9e-33: 127: 19.77		ANK2_HUMAN (28-1012): 2.01e-09: 65.7: 14.82