HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation GO:0019899 - enzyme binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 648
+	Hs
		374280 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374137 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373661 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374734 STRBP_HUMAN (5-176): 5.53e-30: 121: 15.09		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374954 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373946 DSRAD_HUMAN (90-306): 2.7e-29: 120: 16.51		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		322054 STAU1_HUMAN (82-309): 9.84e-10: 61.5: 17.54		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		488699 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		412158 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		FYN_HUMAN (337-607): 2.33e-103: 326: 34.55