Protein: MK
Midkine (MK) (Amphiregulin-associated protein) (ARAP) (Midgestation and kidney protein) (Neurite outgrowth-promoting factor 2) (Neurite outgrowth-promoting protein)

Gene: MK, MDK
Organism: Homo sapiens
Interactions: 78
UniProt ID: P21741

Gene Ontology (top 5):
GO:0001662 - behavioral fear response
GO:0002232 - leukocyte chemotaxis involved in inflammatory response
GO:0002286 - T cell activation involved in immune response
GO:0002690 - positive regulation of leukocyte chemotaxis
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

600947

AF9
Protein AF-9

2

1

High-throughput

0.628

High

600956

H11
Histone H1.1

2

0

High-throughput

0.602

High

600994

CXXC1
CXXC-type zinc finger protein 1

2

0

High-throughput

0.602

High

373679

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

High-throughput

0.584

High

442778

HCK
Tyrosine-protein kinase HCK

2

0

High-throughput

0.580

High

600949

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

4

High-throughput

0.574

High

600965

CHD9
Chromodomain-helicase-DNA-binding protein 9

2

1

High-throughput

0.574

High

601001

SRRM2
Serine/arginine repetitive matrix protein 2

2

1

High-throughput

0.574

High

600955

SRPK2
SRSF protein kinase 2

1

1

High-throughput

0.569

High

600997

UBQL2
Ubiquilin-2

2

6

High-throughput

0.553

High

601000

UBQL1
Ubiquilin-1

2

6

High-throughput

0.553

High

417934

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

561727

CL3L1
C-C motif chemokine 3-like 1

1

0

High-throughput

0.513

High

600958

NOTC2
Neurogenic locus notch homolog protein 2

1

0

High-throughput

0.513

High

600993

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.513

High

270264

LRP6
Low-density lipoprotein receptor-related protein 6

1

5

Small-scale

0.501

High

600943

PTPRZ
Receptor-type tyrosine-protein phosphatase zeta

1

4

Small-scale

0.501

High

600962

LRP8
Low-density lipoprotein receptor-related protein 8

1

5

Small-scale

0.501

High

600998

ALK
ALK tyrosine kinase receptor

1

1

Small-scale

0.501

High

600992

UBQL4
Ubiquilin-4

1

6

High-throughput

0.494

High

600945

PSB10
Proteasome subunit beta type-10

1

1

High-throughput

0.489

High

600976

SORL
Sortilin-related receptor

1

4

High-throughput

0.489

High

600964

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.486

High

600952

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

345920

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

379012

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

537511

NID1
Nidogen-1

1

4

Small-scale

0.479

High

600961

NID2
Nidogen-2

1

4

Small-scale

0.479

High

600979

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

255502

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

434943

SP1
Transcription factor Sp1

1

0

Small-scale

0.458

High

530147

NCAM1
Neural cell adhesion molecule 1

1

0

Small-scale

0.458

High

600951

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

600954

ACTG
Actin, cytoplasmic 2

1

0

Small-scale

0.458

High

600967

TBA1A
Tubulin alpha-1A chain

1

0

Small-scale

0.458

High

600977

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

600984

TBB2B
Tubulin beta-2B chain

1

0

Small-scale

0.458

High

600995

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

600988

RN167
E3 ubiquitin-protein ligase RNF167

1

1

Small-scale

0.457

High

600946

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

600959

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

5

Small-scale

0.437

High

165625

SET1A
Histone-lysine N-methyltransferase SETD1A

2

0

High-throughput

0.328

High

179018

TNC18
Trinucleotide repeat-containing gene 18 protein

2

0

High-throughput

0.328

High

253536

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

2

0

High-throughput

0.328

High

567635

UBF1
Nucleolar transcription factor 1

2

0

High-throughput

0.328

High

600944

BRD2
Bromodomain-containing protein 2

2

0

High-throughput

0.328

High

600950

CLK2
Dual specificity protein kinase CLK2

2

0

High-throughput

0.328

High

600953

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

0

High-throughput

0.328

High

600960

PPIG
Peptidyl-prolyl cis-trans isomerase G

2

0

High-throughput

0.328

High

600972

BD1L1
Biorientation of chromosomes in cell division protein 1-like 1

2

0

High-throughput

0.328

High

600974

KBTB7
Kelch repeat and BTB domain-containing protein 7

2

0

High-throughput

0.328

High

600981

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

0

High-throughput

0.328

High

600983

RPP25
Ribonuclease P protein subunit p25

2

0

High-throughput

0.328

High

600987

PININ
Pinin

2

0

High-throughput

0.328

High

600989

CWC22
Pre-mRNA-splicing factor CWC22 homolog

2

0

High-throughput

0.328

High

600990

E41L5
Band 4.1-like protein 5

2

0

High-throughput

0.328

High

600996

AFF4
AF4/FMR2 family member 4

2

0

High-throughput

0.328

High

600978

RL36L
Ribosomal protein eL42-like

2

0

High-throughput

0.318

High

600986

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

0

High-throughput

0.318

High

600963

TCEA2
Transcription elongation factor A protein 2

2

0

High-throughput

0.316

High

600966

TMED8
Protein TMED8

2

0

High-throughput

0.316

High

600969

RBFA
Putative ribosome-binding factor A, mitochondrial

2

0

High-throughput

0.316

High

600973

JOS2
Josephin-2

2

0

High-throughput

0.316

High

600980

MID49
Mitochondrial dynamics protein MID49

2

0

High-throughput

0.316

High

600985

AP1M1
AP-1 complex subunit mu-1

2

0

High-throughput

0.316

High

600999

NFU1
NFU1 iron-sulfur cluster scaffold homolog, mitochondrial

2

0

High-throughput

0.316

High

170034

PLS1
Phospholipid scramblase 1

1

0

Small-scale

0.292

High

600957

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.282

High

600948

RL35
Large ribosomal subunit protein uL29

1

0

High-throughput

0.279

Low

600970

NKAP
NF-kappa-B-activating protein

1

0

High-throughput

0.279

Low

600971

CAMKV
CaM kinase-like vesicle-associated protein

1

0

High-throughput

0.279

Low

600982

SIN3A
Paired amphipathic helix protein Sin3a

1

0

High-throughput

0.279

Low

600991

ZCC17
Zinc finger CCHC domain-containing protein 17

1

0

High-throughput

0.279

Low

582063

NUCL
Nucleolin

1

0

Small-scale

0.261

Low

601002

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low

259263

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

1

0

Small-scale

0.249

Low

600968

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.249

Low

600975

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024