HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: SRSF7 (Q16629)
Serine/arginine-rich splicing factor 7 (Splicing factor 9G8) (Splicing factor, arginine/serine-rich 7)
Gene: SRSF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 313 Hs			1 238
+	Hs
		269605 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		269696 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		269707 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		269865 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		RBM4_HUMAN (12-89): 4.44e-14: 72.2: 33.33
+	Hs
		1075630 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05
+	Hs
		853874 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		NCBP2_HUMAN (10-114): 8.08e-26: 100: 23.42
+	Hs
		432677 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		432544 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		585462 E2AK2_HUMAN (36-311): 2.71e-51: 179: 18.50		PABP4_HUMAN (1-95): 5.76e-21: 92.9: 27.00
+	Hs
		474018 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		PAB4L_HUMAN (12-95): 5.81e-17: 80.5: 26.97
+	Hs
		963509 ILF3_HUMAN (7-290): 1.14e-53: 190: 13.71		TIAR_HUMAN (5-97): 6.64e-16: 77.8: 25.51
+	Hs
		474032 DGCR8_HUMAN (1-276): 1.44e-44: 163: 19.42		PAB4L_HUMAN (12-95): 5.81e-17: 80.5: 26.97
+	Hs
		1084428 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		SRSF7_HUMAN (1-238): 6.03e-28: 108: 100.00
+	Hs
		1252777 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		ZCRB1_HUMAN (7-221): 2.04e-28: 108: 22.73
+	Hs
		432877 STRBP_HUMAN (5-176): 5.53e-30: 121: 15.09		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		432958 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		HNRPC_HUMAN (3-186): 3e-24: 99: 22.58
+	Hs
		952147 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		SRSF3_HUMAN (5-154): 2.52e-24: 96.5: 55.33
+	Hs
		992958 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		SRSF1_HUMAN (10-81): 4.51e-21: 90.3: 48.65
+	Hs
		516715 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		PABP1_HUMAN (6-97): 2.16e-19: 88.2: 22.11
+	Hs
		1308781 STAU2_HUMAN (33-309): 3.5e-30: 121: 18.79		RBM4B_HUMAN (12-89): 4.32e-17: 81: 32.05