Protein: CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (C-terminal PDZ ligand of neuronal nitric oxide synthase protein) (Nitric oxide synthase 1 adaptor protein)

Gene: CAPON, NOS1AP
Organism: Homo sapiens
Interactions: 110
UniProt ID: O75052

Gene Ontology (top 5):
GO:0002102 - podosome
GO:0003062 - regulation of heart rate by chemical signal
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

269743

NOS1
Nitric oxide synthase 1

2

0

Small-scale

0.788

High

269765

SCRIB
Protein scribble homolog

2

4

High-throughput

0.776

High

269751

PLK1
Serine/threonine-protein kinase PLK1

4

3

High-throughput

0.699

High

269802

AP2M1
AP-2 complex subunit mu

3

8

High-throughput

0.667

High

269787

NKAP
NF-kappa-B-activating protein

4

0

High-throughput

0.664

High

269768

RNPS1
RNA-binding protein with serine-rich domain 1

3

3

High-throughput

0.662

High

269726

A4
Amyloid-beta precursor protein

1

20

High-throughput

0.647

High

269748

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

2

3

High-throughput

0.628

High

269759

AK17A
A-kinase anchor protein 17A

2

5

High-throughput

0.628

High

269815

DDX41
Probable ATP-dependent RNA helicase DDX41

2

4

High-throughput

0.628

High

269760

1433F
14-3-3 protein eta

2

20

High-throughput

0.611

High

269804

EAF1
ELL-associated factor 1

3

1

High-throughput

0.609

High

217024

MS18B
Protein Mis18-beta

2

0

High-throughput

0.602

High

269735

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

269722

PNPH
Purine nucleoside phosphorylase

2

1

High-throughput

0.576

High

269728

FYN
Tyrosine-protein kinase Fyn

2

20

High-throughput

0.576

High

269733

CH60
60 kDa heat shock protein, mitochondrial

2

1

High-throughput

0.576

High

269786

RYBP
RING1 and YY1-binding protein

2

1

High-throughput

0.576

High

269816

PLAL2
Zinc finger protein PLAGL2

2

2

High-throughput

0.576

High

269807

PININ
Pinin

2

4

High-throughput

0.574

High

269811

ZCC17
Zinc finger CCHC domain-containing protein 17

2

1

High-throughput

0.574

High

269817

RASD1
Dexamethasone-induced Ras-related protein 1

1

4

Small-scale

0.573

High

269806

TRAF4
TNF receptor-associated factor 4

1

9

High-throughput

0.573

High

269729

KCRM
Creatine kinase M-type

2

0

High-throughput

0.551

High

269793

ZCH10
Zinc finger CCHC domain-containing protein 10

2

2

High-throughput

0.549

High

209167

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

4

High-throughput

0.536

High

269724

FRIL
Ferritin light chain

1

1

High-throughput

0.536

High

269734

RALA
Ras-related protein Ral-A

1

15

High-throughput

0.536

High

269746

SYUA
Alpha-synuclein

1

2

High-throughput

0.536

High

269754

FGF12
Fibroblast growth factor 12

1

5

High-throughput

0.536

High

269777

KLC3
Kinesin light chain 3

1

6

High-throughput

0.536

High

269790

CAMKV
CaM kinase-like vesicle-associated protein

1

5

High-throughput

0.536

High

269794

PI42C
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma

1

3

High-throughput

0.536

High

269797

ING5
Inhibitor of growth protein 5

1

2

High-throughput

0.536

High

269800

FGF11
Fibroblast growth factor 11

1

5

High-throughput

0.536

High

269803

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

1

High-throughput

0.536

High

269810

E41L1
Band 4.1-like protein 1

1

4

High-throughput

0.536

High

269761

LRP1
Prolow-density lipoprotein receptor-related protein 1

1

20

Small-scale

0.527

High

269812

NHP2
H/ACA ribonucleoprotein complex subunit 2

2

1

High-throughput

0.526

High

269721

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.513

High

269736

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.513

High

269792

RP9
Retinitis pigmentosa 9 protein

1

0

High-throughput

0.513

High

269795

TP4AP
Short transient receptor potential channel 4-associated protein

1

0

High-throughput

0.513

High

269814

IKBL1
NF-kappa-B inhibitor-like protein 1

1

0

High-throughput

0.513

High

269739

SYN1
Synapsin-1

1

8

Small-scale

0.512

High

174183

SYN3
Synapsin-3

1

5

Small-scale

0.501

High

269774

PTPRN
Receptor-type tyrosine-protein phosphatase-like N

1

11

Small-scale

0.501

High

269799

SYN2
Synapsin-2

1

5

Small-scale

0.501

High

269773

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.493

High

269744

CD6
T-cell differentiation antigen CD6

1

1

High-throughput

0.489

High

269747

TFPI2
Tissue factor pathway inhibitor 2

1

15

High-throughput

0.489

High

269749

RAB5C
Ras-related protein Rab-5C

1

6

High-throughput

0.489

High

269785

PLCD3
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3

1

4

High-throughput

0.489

High

269758

LRP2
Low-density lipoprotein receptor-related protein 2

1

20

Small-scale

0.481

High

269764

LRP8
Low-density lipoprotein receptor-related protein 8

1

20

Small-scale

0.481

High

172321

XPO1
Exportin-1

1

5

High-throughput

0.479

High

189341

STX7
Syntaxin-7

1

3

High-throughput

0.479

High

225881

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

259199

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

269718

AUXI
Auxilin

1

4

High-throughput

0.479

High

269719

FLOT1
Flotillin-1

1

3

High-throughput

0.479

High

269720

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

3

High-throughput

0.479

High

269723

RASK
GTPase KRas

1

15

High-throughput

0.479

High

269725

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.479

High

269727

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.479

High

269730

CLCA
Clathrin light chain A

1

5

High-throughput

0.479

High

269731

CLCB
Clathrin light chain B

1

5

High-throughput

0.479

High

269738

CXA1
Gap junction alpha-1 protein

1

5

High-throughput

0.479

High

269741

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

269750

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

269752

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.479

High

269753

RAC3
Ras-related C3 botulinum toxin substrate 3

1

18

High-throughput

0.479

High

269755

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

269756

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

269757

AP2B1
AP-2 complex subunit beta

1

20

High-throughput

0.479

High

269763

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

2

High-throughput

0.479

High

269766

BRD3
Bromodomain-containing protein 3

1

2

High-throughput

0.479

High

269767

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.479

High

269770

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.479

High

269771

NTRK2
BDNF/NT-3 growth factors receptor

1

20

High-throughput

0.479

High

269782

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

269796

SMAP2
Stromal membrane-associated protein 2

1

6

High-throughput

0.479

High

269798

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

269808

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

269818

FBW1A
F-box/WD repeat-containing protein 1A

1

7

High-throughput

0.479

High

247556

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

269778

MEX3B
RNA-binding protein MEX3B

1

0

High-throughput

0.458

High

269813

AATF
Protein AATF

1

0

High-throughput

0.458

High

269745

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

1

High-throughput

0.445

High

269737

RHOQ
Rho-related GTP-binding protein RhoQ

1

19

High-throughput

0.437

High

269742

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.437

High

269762

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

9

High-throughput

0.437

High

269769

RHOH
Rho-related GTP-binding protein RhoH

1

18

High-throughput

0.437

High

269772

OCLN
Occludin

1

2

High-throughput

0.437

High

269776

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

269779

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

269801

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

269809

RHOJ
Rho-related GTP-binding protein RhoJ

1

19

High-throughput

0.437

High

58773

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.407

High

269788

F133A
Protein FAM133A

2

0

High-throughput

0.335

High

269740

MK
Midkine

2

0

High-throughput

0.328

High

269780

NKAP1
Uncharacterized protein NKAPD1

2

0

High-throughput

0.328

High

269781

RHEX
Regulator of hemoglobinization and erythroid cell expansion protein

2

0

High-throughput

0.328

High

269789

SR1IP
Protein SREK1IP1

2

0

High-throughput

0.328

High

269791

GP156
Probable G-protein coupled receptor 156

2

0

High-throughput

0.328

High

269775

AKND1
Protein AKNAD1

2

0

High-throughput

0.300

High

269783

SULF2
Extracellular sulfatase Sulf-2

1

0

High-throughput

0.279

Low

269784

ENTD1
ENTH domain-containing protein 1

1

0

High-throughput

0.279

Low

269805

MMTA2
Multiple myeloma tumor-associated protein 2

1

0

High-throughput

0.279

Low

269732

CT456
Cancer/testis antigen family 45 member A6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025