HitPredict

Interactor 1: RPC9 (O75575)
DNA-directed RNA polymerase III subunit RPC9 (RNA polymerase III subunit C9) (Calcitonin gene-related peptide-receptor component protein) (CGRP-RCP) (CGRP-receptor component protein) (CGRPRCP) (HsC17)
Gene: CRCP

Interactor 2: RPC2 (Q9NW08)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)
Gene: POLR3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	24981860, 35271311, 33674783
Identification Methods	affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003899 - DNA-directed 5'-3' RNA polymerase activity GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex GO:0005829 - cytosol GO:0045087 - innate immune response and 1 others more... GO:0051607 - defense response to virus
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 148 Hs			1 1133
+	Hs
		270182 RPC9_HUMAN (1-148): 1.67e-51: 162: 100.00		RPB2_HUMAN (14-1127): 0: 1475: 37.52
+	Sc
		606690 RPC9_YEAST (1-121): 7.23e-30: 107: 28.93		RPC2_YEAST (12-1130): 0: 1471: 62.84
+	Hs
		270220 RPC9_HUMAN (1-148): 1.67e-51: 162: 100.00		RPA2_HUMAN (36-1128): 0: 1159: 29.59