HitPredict

Interactor 1: LIPA3 (O75145)
Liprin-alpha-3 (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-3) (PTPRF-interacting protein alpha-3)
Gene: PPFIA3

Interactor 2: PTPRF (P10586)
Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)
Gene: PTPRF

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	9624153
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	SAM_1~Y_phosphatase
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1194 Hs			1 1907
+	Hs
		271623 LIPA3_HUMAN (1-1194): 0: 565: 100.00		PTPRS_HUMAN (1-1907): 0: 1569: 65.52
+	Hs
		271614 LIPA3_HUMAN (1-1194): 0: 565: 100.00		PTPRD_HUMAN (29-1907): 0: 1562: 69.67
+	Hs
		522656 LIPA1_HUMAN (1-1194): 6.95e-130: 429: 57.54		PTPRF_HUMAN (1-1907): 0: 1645: 100.00
+	Hs
		276359 LIPA2_HUMAN (1-1194): 2.2e-128: 426: 55.28		PTPRF_HUMAN (1-1907): 0: 1645: 100.00
+	Hs
		1095523 LIPA1_HUMAN (1-1194): 6.95e-130: 429: 57.54		PTPRS_HUMAN (1-1907): 0: 1569: 65.52
+	Hs
		276369 LIPA2_HUMAN (1-1194): 2.2e-128: 426: 55.28		PTPRS_HUMAN (1-1907): 0: 1569: 65.52
+	Hs
		658880 LIPA1_HUMAN (1-1194): 6.95e-130: 429: 57.54		PTPRD_HUMAN (29-1907): 0: 1562: 69.67
+	Hs
		276361 LIPA2_HUMAN (1-1194): 2.2e-128: 426: 55.28		PTPRD_HUMAN (29-1907): 0: 1562: 69.67
+	Dm
		68354 A8DYM0_DROME (820-1158): 2.87e-103: 355: 33.81		LAR_DROME (1-1366): 3.12e-166: 561: 32.76
+	Dm
		598302 Q9VM93_DROME (1-1118): 4.44e-78: 283: 36.74		LAR_DROME (1-1366): 3.12e-166: 561: 32.76
+	Dm
		120098 M9PCD4_DROME (1-1118): 1.76e-77: 281: 36.09		LAR_DROME (1-1366): 3.12e-166: 561: 32.76