HitPredict

Interactor 1: OFD1 (O75665)
Centriole and centriolar satellite protein OFD1 (Oral-facial-digital syndrome 1 protein) (Protein 71-7A)
Gene: OFD1

Interactor 2: LATS1 (O95835)
Serine/threonine-protein kinase LATS1 (EC 2.7.11.1) (Large tumor suppressor homolog 1) (WARTS protein kinase) (h-warts)
Gene: LATS1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1012 Hs			1 1130
+	Hs
		272730 OFD1_HUMAN (1-1012): 1.82e-122: 400: 100.00		LATS2_HUMAN (13-1121): 0: 751: 49.61
+	Hs
		325955 MYH4_HUMAN (29-982): 2.52e-32: 138: 10.84		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325611 MYH6_HUMAN (17-925): 4.1e-27: 121: 11.27		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325936 MYH13_HUMAN (3-735): 1.64e-21: 103: 11.60		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325935 MYH2_HUMAN (15-748): 8.57e-20: 97.8: 10.71		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325608 MYH1_HUMAN (17-582): 6.6e-17: 88.6: 10.09		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		325612 MYH8_HUMAN (57-582): 7.95e-17: 88.2: 13.31		LATS1_HUMAN (1-1130): 0: 934: 100.00
+	Hs
		149340 CTRO_HUMAN (97-647): 2.57e-17: 90.1: 15.29		LATS2_HUMAN (13-1121): 0: 751: 49.61
+	Hs
		272500 OFD1_HUMAN (1-1012): 1.82e-122: 400: 100.00		AKT1_HUMAN (595-1081): 5.84e-141: 435: 24.50
+	Hs
		610802 MYH4_HUMAN (29-982): 2.52e-32: 138: 10.84		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		528359 MYH6_HUMAN (17-925): 4.1e-27: 121: 11.27		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		682219 MYO5A_HUMAN (104-658): 3.36e-17: 89.7: 11.88		AKT2_HUMAN (603-1075): 3.93e-140: 433: 25.31
+	Hs
		610795 MYH2_HUMAN (15-748): 8.57e-20: 97.8: 10.71		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		522538 MYH1_HUMAN (17-582): 6.6e-17: 88.6: 10.09		KAPCB_HUMAN (661-1055): 5.19e-133: 410: 31.58
+	Hs
		1137917 MRCKB_HUMAN (116-621): 1.91e-20: 100: 11.58		MRCKA_HUMAN (694-1047): 2.92e-66: 248: 39.06
+	Rn
		222476 MRCKB_RAT (113-627): 1.46e-21: 103: 11.26		MRCKA_RAT (694-1047): 1.29e-65: 245: 38.78
+	Rn
		1186812 MRCKB_RAT (113-627): 1.46e-21: 103: 11.26		MRCKB_RAT (695-1047): 2.19e-62: 235: 38.06
+	Rn
		222472 MRCKA_RAT (97-525): 2.81e-17: 89.7: 12.59		MRCKA_RAT (694-1047): 1.29e-65: 245: 38.78
+	Hs
		1137871 MRCKA_HUMAN (97-525): 3.54e-16: 86.2: 13.05		MRCKA_HUMAN (694-1047): 2.92e-66: 248: 39.06