HitPredict

Interactor 1: BCAR3 (O75815)
Breast cancer anti-estrogen resistance protein 3 (Novel SH2-containing protein 2) (SH2 domain-containing protein 3B)
Gene: BCAR3

Interactor 2: KIF14 (Q15058)
Kinesin-like protein KIF14
Gene: KIF14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008284 - positive regulation of cell population proliferation GO:0016020 - membrane
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 825 Hs			1 1648
+	Hs
		275543 BCAR3_HUMAN (1-825): 0: 867: 100.00		KINH_HUMAN (356-1198): 1.07e-143: 470: 20.59
+	Hs
		433356 YES_HUMAN (2-333): 6.77e-61: 217: 13.14		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		522995 SRC_HUMAN (33-349): 1.87e-59: 213: 13.95		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		412200 FYN_HUMAN (12-349): 2.18e-58: 210: 11.85		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		454833 FGR_HUMAN (24-337): 3.12e-58: 209: 11.91		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		442832 HCK_HUMAN (23-337): 2.51e-51: 190: 12.09		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		433768 LYN_HUMAN (43-348): 2.28e-51: 189: 12.16		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		802846 CRKL_HUMAN (154-385): 1.37e-50: 181: 18.25		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		666115 SHC1_HUMAN (53-256): 2.41e-37: 150: 23.01		KIF14_HUMAN (1-1648): 0: 891: 100.00
+	Hs
		924982 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		KIF3A_HUMAN (348-815): 1.16e-149: 477: 33.61
+	Hs
		924854 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		KI13A_HUMAN (354-1167): 1.66e-124: 433: 33.05
+	Mm
		1119796 GRB2_MOUSE (99-318): 1.11e-50: 178: 19.91		KI26A_MOUSE (64-708): 6.68e-116: 407: 18.37
+	Hs
		924944 GRB2_HUMAN (99-318): 3.63e-50: 177: 19.91		KI26A_HUMAN (47-708): 5.21e-109: 387: 17.53