Protein: RTN1
Reticulon-like protein 1

Gene: RTN1
Organism: Saccharomyces cerevisiae S288C
Interactions: 137
UniProt ID: Q04947

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005794 - Golgi apparatus
GO:0007029 - endoplasmic reticulum organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

454317

CARP
Saccharopepsin

6

3

Small-scale

0.729

High

1050077

RTN1
Reticulon-like protein 1

4

15

Small-scale

0.671

High

525130

HSP71
Heat shock protein SSA1

6

2

High-throughput

0.651

High

1050097

YOP1
Protein YOP1

3

7

Small-scale

0.640

High

1050100

SEY1
Protein SEY1

3

1

Small-scale

0.640

High

1050098

RTN2
Reticulon-like protein 2

3

16

Small-scale

0.636

High

527658

HSP72
Heat shock protein SSA2

3

2

High-throughput

0.624

High

1050094

RDL1
Thiosulfate:glutathione sulfurtransferase

2

0

High-throughput

0.588

High

393320

HSP82
ATP-dependent molecular chaperone HSP82

3

5

High-throughput

0.585

High

818200

SCS2
Vesicle-associated membrane protein-associated protein SCS2

2

8

Small-scale

0.584

High

914900

SC6B1
Protein transport protein SBH1

2

1

Small-scale

0.584

High

922203

PRA1
Prenylated Rab acceptor 1

2

10

Small-scale

0.584

High

546254

SSB1
Ribosome-associated molecular chaperone SSB1

3

2

High-throughput

0.569

High

569420

DPM1
Dolichol-phosphate mannosyltransferase

2

0

Small-scale

0.559

High

850205

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.559

High

1050092

POM33
Pore membrane protein of 33 kDa

2

0

Small-scale

0.559

High

742383

HSP7F
Heat shock protein homolog SSE1

2

4

High-throughput

0.521

High

751121

PDR5
Pleiotropic ABC efflux transporter of multiple drugs

1

0

High-throughput

0.518

High

806444

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

Small-scale

0.493

High

817953

IMB4
Importin subunit beta-4

1

2

Small-scale

0.489

High

924272

RHO5
GTP-binding protein RHO5

1

8

Small-scale

0.481

High

376344

YPT1
GTP-binding protein YPT1

1

13

Small-scale

0.479

High

510812

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

528637

CP51
Lanosterol 14-alpha demethylase CYP51

1

5

Small-scale

0.479

High

580057

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

597996

NCPR
NADPH--cytochrome P450 reductase

1

4

Small-scale

0.479

High

647222

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

668956

ERG6
Sterol 24-C-methyltransferase ERG6

1

1

Small-scale

0.479

High

680058

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

735321

ERG2
C-8 sterol isomerase ERG2

1

2

High-throughput

0.479

High

735359

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

1

High-throughput

0.479

High

735866

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

3

Small-scale

0.479

High

746944

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

3

High-throughput

0.479

High

785976

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.479

High

795209

NU170
Nucleoporin NUP170

1

3

High-throughput

0.479

High

800919

NCB5R
NADH-cytochrome b5 reductase 1

1

5

Small-scale

0.479

High

812649

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

814384

NOC2
Nucleolar complex protein 2

1

1

High-throughput

0.479

High

822341

ELO3
Fatty acid elongase 3

1

2

High-throughput

0.479

High

881439

TOM22
Mitochondrial import receptor subunit TOM22

1

1

High-throughput

0.479

High

918685

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

Small-scale

0.479

High

925386

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

1025037

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.479

High

1044147

GIS1
Transcriptional activator/repressor GIS1

1

2

High-throughput

0.479

High

1050085

NVJ2
Nucleus-vacuole junction protein 2

1

6

High-throughput

0.479

High

1050087

YET3
Endoplasmic reticulum transmembrane protein 3

1

4

Small-scale

0.479

High

1050089

AP3D
AP-3 complex subunit delta

1

6

High-throughput

0.479

High

1050090

TYW1
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase

1

5

High-throughput

0.479

High

1050093

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

Small-scale

0.479

High

1050101

ENV10
SRP-independent targeting protein 2

1

4

High-throughput

0.479

High

1050086

LEC1
PX domain-containing protein LEC1

1

0

Small-scale

0.460

High

368055

ENO2
Enolase 2

1

0

High-throughput

0.458

High

554447

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

0

Small-scale

0.458

High

705222

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

715049

ERG9
Squalene synthase ERG9

1

0

Small-scale

0.458

High

737588

ERG1
Squalene epoxidase ERG1

1

0

Small-scale

0.458

High

778239

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.458

High

780800

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.458

High

797054

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

802017

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

0

High-throughput

0.458

High

803684

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

804826

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.458

High

826279

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.458

High

844609

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

918286

YG1I
Uncharacterized membrane protein YGR026W

1

0

High-throughput

0.458

High

924147

ALG9
Alpha-1,2-mannosyltransferase ALG9

1

0

High-throughput

0.458

High

1035373

TOF2
Topoisomerase 1-associated factor 2

1

0

Small-scale

0.458

High

1042488

PEX29
Peroxisomal membrane protein PEX29

1

0

Small-scale

0.458

High

1046300

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

1049981

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

0

High-throughput

0.458

High

1050080

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

1050082

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.458

High

752722

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

763021

SPT7
SAGA complex subunit SPT7

1

2

High-throughput

0.445

High

645117

EPT1
Choline/ethanolaminephosphotransferase 1

1

0

High-throughput

0.438

High

744719

GPT1
Glycerol-3-phosphate O-acyltransferase 1

1

0

High-throughput

0.438

High

797859

FTH1
Iron transporter FTH1

1

0

High-throughput

0.438

High

1045186

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.438

High

365186

KPYK1
Pyruvate kinase 1

1

2

High-throughput

0.437

High

444797

SIR2
NAD-dependent histone deacetylase SIR2

1

1

Small-scale

0.437

High

727306

HS104
Heat shock protein 104

1

3

High-throughput

0.437

High

747576

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

752989

IXR1
Intrastrand cross-link recognition protein

1

2

Small-scale

0.437

High

778531

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

795531

ATG8
Autophagy-related protein 8

1

6

High-throughput

0.437

High

864825

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.437

High

918991

PESC
Pescadillo homolog

1

1

High-throughput

0.437

High

1042228

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

394900

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

671708

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

623013

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.417

High

807742

ATC2
Calcium-transporting ATPase 2

1

4

High-throughput

0.417

High

804449

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.407

High

738560

NDC1
Nucleoporin NDC1

2

0

Small-scale

0.323

High

671118

SIS1
Protein SIS1

2

0

High-throughput

0.305

High

758019

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.282

High

1050091

NUR1
Nuclear rim protein 1

1

0

High-throughput

0.282

High

792944

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.279

Low

816149

HAT2
Histone acetyltransferase type B subunit 2

1

0

High-throughput

0.279

Low

893340

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.279

Low

623948

MYO2
Myosin-2

1

0

Small-scale

0.251

Low

433847

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

435357

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.249

Low

442111

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

455260

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

477632

MYO1
Myosin-1

1

0

Small-scale

0.249

Low

503239

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

504414

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

512650

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

513216

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

558866

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

672944

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.249

Low

708166

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709978

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

737946

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.249

Low

746076

SEC6
Exocyst complex component SEC6

1

0

Small-scale

0.249

Low

750780

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

764154

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

800822

RCK2
Serine/threonine-protein kinase RCK2

1

0

High-throughput

0.249

Low

803168

ECM29
Proteasome component ECM29

1

0

High-throughput

0.249

Low

806817

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

826829

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

874527

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

877906

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low

1033564

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

1050081

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

1050083

SEC10
Exocyst complex component SEC10

1

0

Small-scale

0.249

Low

1050084

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.249

Low

1050088

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

1050095

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.249

Low

1050096

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

1050099

POM34
Nucleoporin POM34

1

0

Small-scale

0.249

Low

1050079

NUP59
Nucleoporin ASM4

1

0

High-throughput

0.238

Low

358336

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

592498

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

1050078

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025