Interactor 1: PIAS1 (O75925)
E3 SUMO-protein ligase PIAS1 (EC 2.3.2.-) (DEAD/H box-binding protein 1) (E3 SUMO-protein transferase PIAS1) (Gu-binding protein) (GBP) (Protein inhibitor of activated STAT protein 1) (RNA helicase II-binding protein)
Gene: PIAS1

Interactor 2: KLF3 (P57682)
Krueppel-like factor 3 (Basic krueppel-like factor) (CACCC-box-binding protein BKLF) (TEF-2)
Gene: KLF3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.57 0.60 0.586

The method score is based on:

Property Details
Experiments 30217970, 38297188
Identification Methods two hybrid, proximity labelling technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005654 - nucleoplasm
GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 651
Hs

1 345
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024