HitPredict

Interactor 1: NCOR1 (O75376)
Nuclear receptor corepressor 1 (N-CoR) (N-CoR1)
Gene: NCOR1

Interactor 2: COR2A (Q92828)
Coronin-2A (IR10) (WD repeat-containing protein 2)
Gene: CORO2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.640

Property	Details
Experiments	12628926, 14527417, 21331046
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017053 - transcription repressor complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2440 Hs			1 525
+	Hs
		278401 NCOR1_HUMAN (1-2440): 0: 760: 100.00		SNR40_HUMAN (119-406): 1.34e-58: 199: 16.33
+	Hs
		261354 NCOR1_HUMAN (1-2440): 0: 760: 100.00		TBL1X_HUMAN (80-222): 4.98e-13: 73.6: 30.46
+	Hs
		278423 NCOR1_HUMAN (1-2440): 0: 760: 100.00		TBL1R_HUMAN (80-222): 7.15e-13: 72.8: 29.14
+	Hs
		278417 NCOR1_HUMAN (1-2440): 0: 760: 100.00		TBL1Y_HUMAN (80-222): 1.54e-12: 71.6: 29.80
+	Hs
		1387667 NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91		SNR40_HUMAN (119-406): 1.34e-58: 199: 16.33
+	Hs
		1450956 NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91		NLE1_HUMAN (108-388): 1.52e-47: 174: 15.32
+	Hs
		772939 MYH9_HUMAN (14-581): 1.85e-42: 174: 10.59		COR2A_HUMAN (1-525): 2.08e-150: 442: 100.00
+	Xl
		1274156 NCOR1_XENLA (1-2440): 2.08e-150: 525: 61.86		TB1RA_XENLA (80-222): 9.67e-13: 72.4: 29.14
+	Hs
		1159062 NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91		RBBP7_HUMAN (68-346): 8.55e-38: 145: 16.61
+	Hs
		261459 NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91		TBL1X_HUMAN (80-222): 4.98e-13: 73.6: 30.46
+	Hs
		1410253 NCOR2_HUMAN (1-2439): 1.88e-124: 442: 32.91		TBL1Y_HUMAN (80-222): 1.54e-12: 71.6: 29.80
+	Xl
		1169457 Q1W3Z6_XENLA (5-2439): 2.48e-109: 393: 33.87		TB1RA_XENLA (80-222): 9.67e-13: 72.4: 29.14
+	Hs
		1129693 MDC1_HUMAN (683-2424): 9.89e-54: 211: 10.66		SNR40_HUMAN (119-406): 1.34e-58: 199: 16.33
+	Hs
		1387512 MINT_HUMAN (13-2436): 7.59e-52: 205: 9.42		SNR40_HUMAN (119-406): 1.34e-58: 199: 16.33
+	Hs
		1403515 MINT_HUMAN (13-2436): 7.59e-52: 205: 9.42		NLE1_HUMAN (108-388): 1.52e-47: 174: 15.32
+	Hs
		1158970 MINT_HUMAN (13-2436): 7.59e-52: 205: 9.42		RBBP7_HUMAN (68-346): 8.55e-38: 145: 16.61
+	Dm
		1377808 Q9VYK0_DROME (144-534): 8.7e-71: 268: 35.35		EBI_DROME (80-222): 6.76e-11: 67: 29.14
+	Hs
		261455 RCOR1_HUMAN (360-717): 6.94e-75: 260: 19.40		TBL1X_HUMAN (80-222): 4.98e-13: 73.6: 30.46
+	Mm
		1296649 Q8BK32_MOUSE (1-289): 5.82e-68: 233: 91.72		TBL1R_MOUSE (80-222): 7.21e-13: 72.8: 29.14
+	Mm
		1296853 Q8BK32_MOUSE (1-289): 5.82e-68: 233: 91.72		TBL1X_MOUSE (80-222): 1.9e-12: 71.6: 28.48