HitPredict

Interactor 1: ULK1 (O75385)
Serine/threonine-protein kinase ULK1 (EC 2.7.11.1) (Autophagy-related protein 1 homolog) (ATG1) (hATG1) (Unc-51-like kinase 1)
Gene: ULK1

Interactor 2: GBRAP (O95166)
Gamma-aminobutyric acid receptor-associated protein (GABA(A) receptor-associated protein) (MM46)
Gene: GABARAP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	0.60	0.746

Property	Details
Experiments	17353931, 11146101, 25126726, 28253953, 37658135, 23043107, 20562859
Identification Methods	affinity chromatography technology, two hybrid, pull down, unspecified method, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0000421 - autophagosome membrane GO:0000423 - mitophagy GO:0005776 - autophagosome GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1050 Hs			1 117
+	Hs
		279139 ULK1_HUMAN (1-1050): 0: 814: 100.00		GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27
+	Hs
		279220 ULK1_HUMAN (1-1050): 0: 814: 100.00		GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07
+	Hs
		279223 ULK1_HUMAN (1-1050): 0: 814: 100.00		MLP3A_HUMAN (5-117): 2.3e-45: 144: 30.44
+	Hs
		279216 ULK1_HUMAN (1-1050): 0: 814: 100.00		MLP3C_HUMAN (5-116): 1.16e-44: 143: 38.60
+	Hs
		279219 ULK1_HUMAN (1-1050): 0: 814: 100.00		MLP3B_HUMAN (2-117): 3.56e-44: 141: 30.51
+	Hs
		952238 ULK2_HUMAN (9-1044): 0: 694: 50.38		GBRL2_HUMAN (1-117): 2.76e-58: 176: 57.27
+	Hs
		328067 ULK2_HUMAN (9-1044): 0: 694: 50.38		GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00
+	Hs
		1315552 ULK2_HUMAN (9-1044): 0: 694: 50.38		GBRL1_HUMAN (1-116): 8.18e-56: 170: 87.07
+	Hs
		1315551 ULK2_HUMAN (9-1044): 0: 694: 50.38		MLP3B_HUMAN (2-117): 3.56e-44: 141: 30.51
+	Hs
		328151 SLK_HUMAN (7-1015): 3.78e-129: 424: 14.01		GBRAP_HUMAN (1-117): 8.09e-57: 173: 100.00
+	Dm
		1320960 Q8MQJ7_DROME (646-1044): 2.01e-119: 389: 25.92		Q9W2S2_DROME (1-117): 5.31e-58: 176: 91.45
+	Ce
		1067974 UNC51_CAEEL (477-1044): 7.36e-80: 281: 21.38		LGG1_CAEEL (1-116): 2.48e-55: 170: 83.62
+	Sc
		795460 ATG1_YEAST (16-273): 4.52e-46: 181: 37.12		ATG8_YEAST (1-116): 9.22e-59: 178: 55.17