Interactor 1: SC22B (O75396)
Vesicle-trafficking protein SEC22b (ER-Golgi SNARE of 24 kDa) (ERS-24) (ERS24) (SEC22 vesicle-trafficking protein homolog B) (SEC22 vesicle-trafficking protein-like 1)
Gene: SEC22B
Interactor 2: STX4 (Q12846)
Syntaxin-4 (Renal carcinoma antigen NY-REN-31)
Gene: STX4
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.78 | 1.00 | 0.883 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 34079125, unassigned1304, 22153078 |
| Identification Methods | two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti bait coimmunoprecipitation |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SNARE~Synaptobrevin, Synaptobrevin~Syntaxin |
| Common GO terms | GO:0005484 - SNAP receptor activity GO:0030670 - phagocytic vesicle membrane |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025