HitPredict

Interactor 1: GGYF1 (O75420)
GRB10-interacting GYF protein 1 (PERQ amino acid-rich with GYF domain-containing protein 1)
Gene: GIGYF1

Interactor 2: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	23444366, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1035 Hs			1 245
+	Hs
		281304 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		281305 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		281289 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Mm
		972306 GGYF1_MOUSE (1-1035): 0: 998: 86.43		1433E_MOUSE (2-243): 1.32e-144: 406: 63.53
+	Hs
		281290 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		281309 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		281303 GGYF1_HUMAN (1-1035): 0: 1030: 100.00		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Hs
		971673 GGYF2_HUMAN (538-1035): 1.19e-65: 244: 27.03		1433E_HUMAN (2-243): 1.32e-144: 406: 63.53
+	Hs
		990381 GGYF2_HUMAN (538-1035): 1.19e-65: 244: 27.03		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		729974 GGYF2_HUMAN (538-1035): 1.19e-65: 244: 27.03		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		1049453 GGYF2_HUMAN (538-1035): 1.19e-65: 244: 27.03		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43
+	Hs
		966498 GGYF2_HUMAN (538-1035): 1.19e-65: 244: 27.03		1433G_HUMAN (1-242): 5.51e-105: 305: 70.33
+	Mm
		990062 PLEC_MOUSE (511-899): 1.03e-11: 71.6: 10.47		1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00
+	Hs
		691026 PLEC_HUMAN (511-823): 8.17e-12: 72: 10.90		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		990250 PLEC_HUMAN (511-823): 8.17e-12: 72: 10.90		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		691529 MYH13_HUMAN (491-976): 2.39e-10: 67: 11.61		1433T_HUMAN (1-245): 9.51e-142: 398: 100.00
+	Hs
		990856 MYH13_HUMAN (491-976): 2.39e-10: 67: 11.61		1433Z_HUMAN (1-245): 1.76e-141: 397: 79.59
+	Hs
		729828 DCTN1_HUMAN (329-792): 3.11e-09: 63.5: 13.14		1433B_HUMAN (1-242): 5.04e-139: 391: 81.82
+	Hs
		730598 PLEC_HUMAN (511-823): 8.17e-12: 72: 10.90		1433S_HUMAN (1-236): 9.9e-108: 312: 71.85
+	Hs
		1049311 PLEC_HUMAN (511-823): 8.17e-12: 72: 10.90		1433F_HUMAN (2-242): 7.19e-106: 307: 71.43