HitPredict

Interactor 1: NEUL1 (O76050)
E3 ubiquitin-protein ligase NEURL1 (EC 2.3.2.27) (Neuralized-like protein 1A) (h-neu) (h-neuralized 1) (RING finger protein 67) (RING-type E3 ubiquitin transferase NEURL1)
Gene: NEURL1

Interactor 2: UB2D1 (P51668)
Ubiquitin-conjugating enzyme E2 D1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D1) (Stimulator of Fe transport) (SFT) (UBC4/5 homolog) (UbcH5) (Ubiquitin carrier protein D1) (Ubiquitin-conjugating enzyme E2(17)KB 1) (Ubiquitin-conjugating enzyme E2-17 kDa 1) (Ubiquitin-protein ligase D1)
Gene: UBE2D1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	18077452
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4_3
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 574 Hs			1 147
+	Hs
		282380 NEUL1_HUMAN (1-574): 0: 699: 100.00		UBE2N_HUMAN (4-147): 1.92e-68: 205: 45.83
+	Mm
		56811 A2A5J5_MOUSE (50-157): 3.34e-35: 135: 32.41		UB2D1_MOUSE (1-147): 3.24e-82: 239: 100.00
+	At
		715118 LUL3_ARATH (414-570): 1.14e-32: 131: 19.62		UBC8_ARATH (1-147): 3.61e-82: 239: 76.19
+	At
		1195870 LUL3_ARATH (414-570): 1.14e-32: 131: 19.62		UBC29_ARATH (1-147): 1.39e-78: 230: 74.15
+	Hs
		230183 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84
+	Hs
		230126 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00
+	Dm
		639392 DIAP1_DROME (440-573): 3.31e-23: 104: 19.40		UBCD1_DROME (1-147): 1.87e-81: 238: 89.12
+	Hs
		230132 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		1316184 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2D4_HUMAN (1-147): 1.29e-82: 241: 91.84
+	Hs
		230131 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44
+	Hs
		895820 MEX3B_HUMAN (455-572): 2.83e-22: 102: 19.12		UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44
+	Hs
		919746 MEX3C_HUMAN (449-572): 3.76e-21: 99.5: 18.38		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		849431 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2D1_HUMAN (1-147): 3.24e-82: 239: 100.00
+	Hs
		919845 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2D2_HUMAN (1-147): 7.7e-82: 238: 89.12
+	Hs
		895808 MEX3C_HUMAN (449-572): 3.76e-21: 99.5: 18.38		UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44
+	Hs
		895897 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2D3_HUMAN (1-147): 9.08e-81: 236: 88.44
+	Zm
		9310 A0A1D6EW17_MAIZE (464-570): 1.71e-21: 100: 28.04		A0A1D6NGW9_MAIZE (1-143): 5.07e-79: 234: 77.62
+	Hs
		230127 MGRN1_HUMAN (464-570): 1.12e-22: 103: 22.43		UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94
+	Hs
		851881 RNF26_HUMAN (439-572): 3.55e-21: 98.4: 19.21		UB2E1_HUMAN (4-146): 3.94e-72: 216: 62.94
+	Hs
		896460 MEX3C_HUMAN (449-572): 3.76e-21: 99.5: 18.38		UBE2N_HUMAN (4-147): 1.92e-68: 205: 45.83