HitPredict - High confidence protein-protein interactions

Interactor 1: O77430 (O77430)
GEO01111p1 (HL01263p) (RH26825p) (SKP1-related A, isoform A) (SKP1-related A, isoform B) (SKP1-related A, isoform C) (SKP1-related A, isoform E) (SKP1-related A, isoform F) (SKP1-related A, isoform G) (SKPA)
Gene: SkpA

Interactor 2: O77430 (O77430)
GEO01111p1 (HL01263p) (RH26825p) (SKP1-related A, isoform A) (SKP1-related A, isoform B) (SKP1-related A, isoform C) (SKP1-related A, isoform E) (SKP1-related A, isoform F) (SKP1-related A, isoform G) (SKPA)
Gene: SkpA

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19079254
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Skp1~Skp1_POZ, Skp1_POZ~Skp1_POZ
Common GO terms	GO:0000278 - mitotic cell cycle GO:0002785 - negative regulation of antimicrobial peptide production GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 21 others more... GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016322 - neuron remodeling GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0030261 - chromosome condensation GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031647 - regulation of protein stability GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0035331 - negative regulation of hippo signaling GO:0042023 - DNA endoreduplication GO:0043066 - negative regulation of apoptotic process GO:0045886 - negative regulation of synaptic assembly at neuromuscular junction GO:0045931 - positive regulation of mitotic cell cycle GO:0046329 - negative regulation of JNK cascade GO:0046627 - negative regulation of insulin receptor signaling pathway GO:0051298 - centrosome duplication GO:0060090 - molecular adaptor activity GO:0061060 - negative regulation of peptidoglycan recognition protein signaling pathway GO:0090090 - negative regulation of canonical Wnt signaling pathway GO:0097602 - cullin family protein binding GO:1905088 - positive regulation of synaptonemal complex assembly
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1	162
Dm

1	162

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Last updated: 15 Jul 2024