HitPredict

Interactor 1: STX11 (O75558)
Syntaxin-11
Gene: STX11

Interactor 2: SNP25 (P60880)
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)
Gene: SNAP25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	16189514, 16169070, 32296183, unassigned1304, unassigned3799
Identification Methods	two hybrid, validated two hybrid, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex GO:0031629 - synaptic vesicle fusion to presynaptic active zone membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 287 Hs			1 206
+	Bt
		746103 STX1A_BOVIN (1-286): 1.04e-71: 224: 28.67		SNP25_BOVIN (1-206): 1.78e-64: 199: 100.00
+	Mm
		204921 STX1A_MOUSE (1-286): 2.39e-71: 223: 28.67		SNP25_MOUSE (1-206): 1.78e-64: 199: 100.00
+	Rn
		746107 STX1A_RAT (1-286): 3.03e-71: 223: 28.67		SNP25_RAT (1-206): 1.78e-64: 199: 100.00
+	Hs
		954380 STX1B_HUMAN (1-286): 1.33e-71: 223: 32.17		SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00
+	Rn
		954423 STX1B_RAT (1-286): 1.33e-71: 223: 32.17		SNP25_RAT (1-206): 1.78e-64: 199: 100.00
+	Hs
		954395 STX1A_HUMAN (1-286): 2.83e-70: 220: 28.67		SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00
+	Hs
		746187 STX2_HUMAN (1-286): 7.66e-68: 214: 31.82		SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00
+	Hs
		124030 STX1B_HUMAN (1-286): 1.33e-71: 223: 32.17		SNP23_HUMAN (12-205): 3e-59: 186: 59.51
+	Ce
		194911 STX1A_CAEEL (2-286): 5.02e-66: 209: 28.42		O62414_CAEEL (1-203): 1.09e-64: 200: 52.20
+	Dm
		788351 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		SNP25_DROME (4-204): 2.9e-62: 194: 60.89
+	Rn
		266931 STX1B_RAT (1-286): 1.33e-71: 223: 32.17		SNP23_RAT (12-205): 1.78e-58: 184: 62.26
+	Hs
		124057 STX1A_HUMAN (1-286): 2.83e-70: 220: 28.67		SNP23_HUMAN (12-205): 3e-59: 186: 59.51
+	Mm
		148586 STX1A_MOUSE (1-286): 2.39e-71: 223: 28.67		SNP23_MOUSE (12-205): 3.53e-58: 183: 62.26
+	Dm
		1174541 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		Q9VH76_DROME (3-205): 1.51e-59: 187: 58.65
+	Hs
		123997 STX2_HUMAN (1-286): 7.66e-68: 214: 31.82		SNP23_HUMAN (12-205): 3e-59: 186: 59.51
+	Hs
		343346 STX1B_HUMAN (1-286): 1.33e-71: 223: 32.17		SNP29_HUMAN (3-202): 6.1e-54: 174: 20.44
+	Hs
		343380 STX1A_HUMAN (1-286): 2.83e-70: 220: 28.67		SNP29_HUMAN (3-202): 6.1e-54: 174: 20.44
+	Mm
		204936 STX1A_MOUSE (1-286): 2.39e-71: 223: 28.67		SNP29_MOUSE (3-202): 1.13e-51: 168: 17.62
+	Hs
		343322 STX2_HUMAN (1-286): 7.66e-68: 214: 31.82		SNP29_HUMAN (3-202): 6.1e-54: 174: 20.44
+	Dm
		1174553 STX1A_DROME (10-286): 7.21e-68: 214: 26.72		Q9W1I8_DROME (2-204): 4.75e-45: 152: 20.80