HitPredict

Interactor 1: SNP29 (O95721)
Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29)
Gene: SNAP29

Interactor 2: STX2 (P32856)
Syntaxin-2 (Epimorphin)
Gene: STX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.606

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0031201 - SNARE complex GO:0031629 - synaptic vesicle fusion to presynaptic active zone membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 258 Hs			1 288
+	Hs
		343346 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX1B_HUMAN (1-287): 6.05e-81: 247: 64.81
+	Mm
		204936 SNP29_MOUSE (1-258): 2.07e-81: 246: 83.08		STX1A_MOUSE (1-287): 5.22e-78: 240: 65.63
+	Hs
		343380 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX1A_HUMAN (1-286): 4.16e-76: 235: 64.46
+	Hs
		343362 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX4_HUMAN (1-286): 1.24e-60: 196: 42.57
+	Hs
		343369 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX3_HUMAN (1-287): 6.28e-60: 194: 63.79
+	Hs
		343513 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		X5D7S1_HUMAN (1-285): 2.5e-59: 191: 55.59
+	Hs
		123997 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX2_HUMAN (1-288): 5.72e-82: 250: 100.00
+	Hs
		124030 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX1B_HUMAN (1-287): 6.05e-81: 247: 64.81
+	Hs
		124057 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX1A_HUMAN (1-286): 4.16e-76: 235: 64.46
+	Hs
		286615 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX11_HUMAN (1-273): 1.05e-51: 172: 31.82
+	Hs
		160857 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX16_HUMAN (3-263): 1.6e-50: 171: 19.55
+	Hs
		189367 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX7_HUMAN (36-284): 1.3e-48: 164: 27.78
+	Hs
		343406 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		STX12_HUMAN (26-270): 4.73e-48: 162: 25.00
+	Hs
		343448 SNP29_HUMAN (1-258): 4.57e-83: 250: 100.00		TSNA1_HUMAN (25-288): 2.22e-45: 161: 18.96
+	Hs
		124045 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX4_HUMAN (1-286): 1.24e-60: 196: 42.57
+	Hs
		124048 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX3_HUMAN (1-287): 6.28e-60: 194: 63.79
+	Hs
		123952 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX11_HUMAN (1-273): 1.05e-51: 172: 31.82
+	Hs
		69431 A8K287_HUMAN (41-258): 1.15e-58: 187: 20.18		STX11_HUMAN (1-273): 1.05e-51: 172: 31.82
+	Hs
		123944 SNP23_HUMAN (41-258): 1.15e-58: 187: 20.18		STX7_HUMAN (36-284): 1.3e-48: 164: 27.78
+	At
		1192496 SNP29_ARATH (1-258): 2.54e-60: 192: 21.85		SY111_ARATH (4-265): 1.42e-44: 155: 21.69