HitPredict

Interactor 1: PRKRA (O75569)
Interferon-inducible double-stranded RNA-dependent protein kinase activator A (PKR-associated protein X) (PKR-associating protein X) (Protein activator of the interferon-induced protein kinase) (Protein kinase, interferon-inducible double-stranded RNA-dependent activator)
Gene: PRKRA

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0042474 - middle ear morphogenesis GO:0048471 - perinuclear region of cytoplasm GO:0048705 - skeletal system morphogenesis
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 454
+	Hs
		372115 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		371896 ILF3_HUMAN (7-290): 1.15e-53: 190: 13.71		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		286848 PRKRA_HUMAN (1-313): 1.21e-119: 348: 100.00		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		371135 E2AK2_HUMAN (36-311): 2.72e-51: 179: 18.50		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		372704 DGCR8_HUMAN (1-276): 1.45e-44: 163: 19.42		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		372917 STRBP_HUMAN (5-176): 5.56e-30: 121: 15.09		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		373269 STAU2_HUMAN (33-309): 3.51e-30: 121: 18.79		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		371576 DSRAD_HUMAN (90-306): 2.71e-29: 120: 16.51		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		406218 TRBP2_HUMAN (18-313): 1.34e-81: 253: 41.08		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		345234 STAU1_HUMAN (82-309): 9.88e-10: 61.5: 17.54		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		406120 ILF3_HUMAN (7-290): 1.15e-53: 190: 13.71		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		405780 E2AK2_HUMAN (36-311): 2.72e-51: 179: 18.50		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		406439 DGCR8_HUMAN (1-276): 1.45e-44: 163: 19.42		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		406537 STRBP_HUMAN (5-176): 5.56e-30: 121: 15.09		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		406702 STAU2_HUMAN (33-309): 3.51e-30: 121: 18.79		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		405944 DSRAD_HUMAN (90-306): 2.71e-29: 120: 16.51		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		406047 RED1_HUMAN (228-306): 5.98e-12: 68.4: 16.46		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		345243 STAU1_HUMAN (82-309): 9.88e-10: 61.5: 17.54		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		346039 STAU1_HUMAN (82-309): 9.88e-10: 61.5: 17.54		MGAP_HUMAN (151-449): 2.43e-27: 118: 17.71