HitPredict

Interactor 1: LRP6 (O75581)
Low-density lipoprotein receptor-related protein 6 (LRP-6)
Gene: LRP6

Interactor 2: RHES (Q96D21)
GTP-binding protein Rhes (Ras homolog enriched in striatum) (Tumor endothelial marker 2)
Gene: RASD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0045202 - synapse
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1613 Hs			1 266
+	Hs
		274908 LRP5_HUMAN (15-1613): 0: 1630: 70.08		RHES_HUMAN (1-266): 3.95e-85: 256: 100.00
+	Hs
		270548 LRP4_HUMAN (1196-1442): 4.6e-32: 139: 27.72		RB11A_HUMAN (10-222): 1.41e-72: 222: 20.80
+	Hs
		976260 LRP8_HUMAN (1288-1611): 2.51e-26: 119: 16.33		RB11A_HUMAN (10-222): 1.41e-72: 222: 20.80
+	Hs
		1022612 LRP2_HUMAN (1383-1612): 1.33e-12: 75.5: 7.88		RAB35_HUMAN (12-195): 3.47e-83: 249: 29.19
+	Hs
		976203 LRP2_HUMAN (1383-1612): 1.33e-12: 75.5: 7.88		RB11A_HUMAN (10-222): 1.41e-72: 222: 20.80
+	Hs
		976224 LRP1_HUMAN (1206-1360): 2.41e-09: 64.7: 19.88		RB11A_HUMAN (10-222): 1.41e-72: 222: 20.80