HitPredict

Interactor 1: PRDM1 (O75626)
PR domain zinc finger protein 1 (EC 2.1.1.-) (BLIMP-1) (Beta-interferon gene positive regulatory domain I-binding factor) (PR domain-containing protein 1) (Positive regulatory domain I-binding factor 1) (PRDI-BF1) (PRDI-binding factor 1)
Gene: PRDM1

Interactor 2: TLE1 (Q04724)
Transducin-like enhancer protein 1 (E(Sp1) homolog) (Enhancer of split groucho-like protein 1) (ESG1)
Gene: TLE1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	9887105, 35140242
Identification Methods	pull down, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0010628 - positive regulation of gene expression
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 825 Hs			1 770
+	Hs
		289140 PRDM1_HUMAN (1-825): 0: 676: 100.00		TLE4_HUMAN (1-770): 0: 571: 86.53
+	Hs
		289139 PRDM1_HUMAN (1-825): 0: 676: 100.00		TLE3_HUMAN (1-770): 1.2e-180: 537: 77.29
+	Hs
		289138 PRDM1_HUMAN (1-825): 0: 676: 100.00		TLE2_HUMAN (1-770): 5.33e-153: 465: 64.33
+	Hs
		289143 PRDM1_HUMAN (1-825): 0: 676: 100.00		TLE5_HUMAN (1-200): 4.92e-91: 285: 64.50
+	Hs
		261355 PRDM1_HUMAN (1-825): 0: 676: 100.00		TBL1X_HUMAN (351-729): 3.13e-75: 256: 12.84
+	Hs
		1061777 ZN383_HUMAN (497-683): 2.94e-76: 257: 31.37		TLE5_HUMAN (1-200): 4.92e-91: 285: 64.50