Interactor 1: GEMI (O88513)
Geminin
Gene: Gmnn

Interactor 2: CDT1 (Q8R4E9)
DNA replication factor Cdt1 (Double parked homolog) (DUP) (Retroviral insertion site 2 protein)
Gene: CDT1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 1.00 0.849

The method score is based on:

Property Details
Experiments 14973489, 15286659, 12192004
Identification Methods affinity chromatography technology, x-ray crystallography, two hybrid, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains CDT1~Geminin
Common GO terms GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0030174 - regulation of DNA-templated DNA replication initiation
GO:0071163 - DNA replication preinitiation complex assembly
GO:2000104 - negative regulation of DNA-templated DNA replication
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 206
Mm

1 557
+ Hs
+ Hs
+ Xl

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024