Protein: STK16
Serine/threonine-protein kinase 16 (EC 2.7.11.1) (Myristoylated and palmitoylated serine/threonine-protein kinase) (MPSK) (Protein kinase PKL12) (TGF-beta-stimulated factor 1) (TSF-1) (Tyrosine-protein kinase STK16) (EC 2.7.10.2) (hPSK)

Gene: STK16
Organism: Homo sapiens
Interactions: 161
UniProt ID: O75716

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0004674 - protein serine/threonine kinase activity
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

291756

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

6

High-throughput

0.783

High

291815

ZN774
Zinc finger protein 774

2

1

High-throughput

0.783

High

291835

TRI42
Tripartite motif-containing protein 42

3

18

High-throughput

0.779

High

291852

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

High-throughput

0.740

High

291877

IKZF3
Zinc finger protein Aiolos

1

3

High-throughput

0.740

High

291839

KCD17
BTB/POZ domain-containing protein KCTD17

4

5

High-throughput

0.705

High

291816

ZN343
Zinc finger protein 343

2

2

High-throughput

0.700

High

291868

PRDM6
Putative histone-lysine N-methyltransferase PRDM6

2

4

High-throughput

0.700

High

291761

CSK
Tyrosine-protein kinase CSK

1

10

High-throughput

0.691

High

291765

IRAK1
Interleukin-1 receptor-associated kinase 1

1

8

High-throughput

0.691

High

291779

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

16

High-throughput

0.691

High

291825

PCAT2
Lysophosphatidylcholine acyltransferase 2

1

9

High-throughput

0.691

High

291769

KR108
Keratin-associated protein 10-8

3

7

High-throughput

0.675

High

291777

REL
Proto-oncogene c-Rel

3

5

High-throughput

0.675

High

291783

INCA1
Protein INCA1

3

1

High-throughput

0.675

High

291870

PLS3
Phospholipid scramblase 3

3

1

High-throughput

0.675

High

270745

ROCK2
Rho-associated protein kinase 2

1

15

High-throughput

0.665

High

291759

VHL
von Hippel-Lindau disease tumor suppressor

1

2

High-throughput

0.665

High

291857

PASK
PAS domain-containing serine/threonine-protein kinase

1

17

High-throughput

0.665

High

291869

SNRK
SNF-related serine/threonine-protein kinase

1

17

High-throughput

0.665

High

291774

CSK2B
Casein kinase II subunit beta

1

3

High-throughput

0.656

High

291775

BORG5
Cdc42 effector protein 1

1

0

High-throughput

0.656

High

291740

STK16
Serine/threonine-protein kinase 16

1

17

Small-scale

0.647

High

291821

ATL4
ADAMTS-like protein 4

4

3

High-throughput

0.642

High

291859

KCD14
BTB/POZ domain-containing protein KCTD14

4

7

High-throughput

0.637

High

291829

NT2NA
Notch homolog 2 N-terminal-like protein A

2

5

High-throughput

0.633

High

291752

FILA
Filaggrin

2

15

High-throughput

0.628

High

291789

TBB3
Tubulin beta-3 chain

2

13

High-throughput

0.628

High

291803

TBB8
Tubulin beta-8 chain

2

13

High-throughput

0.628

High

291810

DCA10
DDB1- and CUL4-associated factor 10

2

5

High-throughput

0.628

High

291885

ATG4B
Cysteine protease ATG4B

2

1

High-throughput

0.628

High

291874

SEC63
Translocation protein SEC63 homolog

1

4

High-throughput

0.618

High

291762

RPIA
Ribose-5-phosphate isomerase

2

0

High-throughput

0.618

High

291791

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

17

High-throughput

0.618

High

291794

MELK
Maternal embryonic leucine zipper kinase

1

16

High-throughput

0.618

High

291742

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

3

2

High-throughput

0.616

High

155058

SOCS2
Suppressor of cytokine signaling 2

2

14

High-throughput

0.606

High

220214

FRS3
Fibroblast growth factor receptor substrate 3

2

4

High-throughput

0.606

High

291764

FXR1
RNA-binding protein FXR1

2

1

High-throughput

0.606

High

291776

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

3

High-throughput

0.606

High

291780

GABPA
GA-binding protein alpha chain

2

1

High-throughput

0.606

High

291781

KRA11
Keratin-associated protein 1-1

2

7

High-throughput

0.606

High

291804

KR132
Keratin-associated protein 13-2

2

1

High-throughput

0.606

High

291811

KPRP
Keratinocyte proline-rich protein

2

1

High-throughput

0.606

High

291828

MIER3
Mesoderm induction early response protein 3

2

5

High-throughput

0.606

High

291833

KRA13
Keratin-associated protein 1-3

2

7

High-throughput

0.606

High

291851

DDT4L
DNA damage-inducible transcript 4-like protein

2

1

High-throughput

0.606

High

291855

PKNX2
Homeobox protein PKNOX2

2

3

High-throughput

0.606

High

291866

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

2

3

High-throughput

0.606

High

291814

BLT3A
Bridge-like lipid transfer protein family member 3A

3

1

High-throughput

0.604

High

291854

MACIR
Macrophage immunometabolism regulator

2

0

High-throughput

0.602

High

291841

RIN3
Ras and Rab interactor 3

2

5

High-throughput

0.601

High

291831

KR131
Keratin-associated protein 13-1

2

1

High-throughput

0.584

High

291787

CBX3
Chromobox protein homolog 3

2

0

High-throughput

0.580

High

291795

K1H1
Keratin, type I cuticular Ha1

2

0

High-throughput

0.580

High

291827

BHA09
Class A basic helix-loop-helix protein 9

2

0

High-throughput

0.580

High

291832

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.580

High

291848

NAA80
N-alpha-acetyltransferase 80

2

0

High-throughput

0.580

High

291883

ZN330
Zinc finger protein 330

2

0

High-throughput

0.580

High

291887

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

0

High-throughput

0.580

High

65992

U119B
Protein unc-119 homolog B

2

0

High-throughput

0.576

High

180454

PLS1
Phospholipid scramblase 1

1

1

High-throughput

0.573

High

221070

SPY2
Protein sprouty homolog 2

1

4

High-throughput

0.573

High

291747

SKIL
Ski-like protein

1

1

High-throughput

0.573

High

291749

TRI27
Zinc finger protein RFP

1

5

High-throughput

0.573

High

291750

ITF2
Transcription factor 4

1

1

High-throughput

0.573

High

291763

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.573

High

291768

KR107
Keratin-associated protein 10-7

1

8

High-throughput

0.573

High

291770

KR109
Keratin-associated protein 10-9

1

8

High-throughput

0.573

High

291786

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

15

High-throughput

0.573

High

291790

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

4

High-throughput

0.573

High

291798

TRIP6
Thyroid receptor-interacting protein 6

1

6

High-throughput

0.573

High

291807

MTUS2
Microtubule-associated tumor suppressor candidate 2

1

10

High-throughput

0.573

High

291846

PCSK5
Proprotein convertase subtilisin/kexin type 5

1

2

High-throughput

0.573

High

291858

HTF4
Transcription factor 12

1

1

High-throughput

0.573

High

291879

DRG1
Developmentally-regulated GTP-binding protein 1

1

2

High-throughput

0.573

High

71075

CSKMT
Citrate synthase-lysine N-methyltransferase CSKMT, mitochondrial

2

1

High-throughput

0.553

High

291754

PROP
Properdin

2

7

High-throughput

0.553

High

291800

RSPO4
R-spondin-4

2

3

High-throughput

0.553

High

291876

NAGK
N-acetyl-D-glucosamine kinase

1

0

Small-scale

0.549

High

209928

CRX
Cone-rod homeobox protein

1

0

High-throughput

0.549

High

225396

CIKS
E3 ubiquitin ligase TRAF3IP2

1

0

High-throughput

0.549

High

291819

KR261
Keratin-associated protein 26-1

1

0

High-throughput

0.549

High

291830

RFX6
DNA-binding protein RFX6

1

0

High-throughput

0.549

High

291856

FACC1
Flagellum-associated coiled-coil domain-containing protein 1

1

0

High-throughput

0.549

High

291863

NIF3L
NIF3-like protein 1

1

0

High-throughput

0.549

High

291744

TBB5
Tubulin beta chain

1

13

High-throughput

0.536

High

291745

CLCB
Clathrin light chain B

1

7

High-throughput

0.536

High

291748

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

4

High-throughput

0.536

High

291755

AL4A1
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial

1

1

High-throughput

0.536

High

291758

MCM7
DNA replication licensing factor MCM7

1

7

High-throughput

0.536

High

291771

UBC12
NEDD8-conjugating enzyme Ubc12

1

8

High-throughput

0.536

High

291785

TP53B
TP53-binding protein 1

1

4

High-throughput

0.536

High

291792

DOCK1
Dedicator of cytokinesis protein 1

1

14

High-throughput

0.536

High

291793

MCM6
DNA replication licensing factor MCM6

1

10

High-throughput

0.536

High

291799

OCLN
Occludin

1

1

High-throughput

0.536

High

291805

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

1

High-throughput

0.536

High

291824

TBA1A
Tubulin alpha-1A chain

1

13

High-throughput

0.536

High

291834

CHERP
Calcium homeostasis endoplasmic reticulum protein

1

2

High-throughput

0.536

High

291844

ELYS
Protein ELYS

1

6

High-throughput

0.536

High

291845

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

3

High-throughput

0.536

High

291847

GSLG1
Golgi apparatus protein 1

1

2

High-throughput

0.536

High

291860

TBA1C
Tubulin alpha-1C chain

1

14

High-throughput

0.536

High

291862

SPY4
Protein sprouty homolog 4

1

4

High-throughput

0.536

High

291878

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

1

High-throughput

0.536

High

291886

BIG2
Brefeldin A-inhibited guanine nucleotide-exchange protein 2

1

3

High-throughput

0.536

High

291850

MAL2
Protein MAL2

1

0

Small-scale

0.529

High

291808

EFHC2
EF-hand domain-containing family member C2

1

4

High-throughput

0.523

High

291772

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.519

High

291760

HNF4A
Hepatocyte nuclear factor 4-alpha

1

9

High-throughput

0.515

High

291797

TGIF1
Homeobox protein TGIF1

1

2

High-throughput

0.515

High

291767

KR105
Keratin-associated protein 10-5

1

10

High-throughput

0.515

High

291757

RIR2
Ribonucleoside-diphosphate reductase subunit M2

1

0

High-throughput

0.513

High

291784

WASC5
WASH complex subunit 5

1

0

High-throughput

0.513

High

291812

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.513

High

291818

CNNM4
Metal transporter CNNM4

1

0

High-throughput

0.513

High

291822

FBX50
F-box only protein 50

1

0

High-throughput

0.513

High

291837

INT1
Integrator complex subunit 1

1

0

High-throughput

0.513

High

291840

MROH1
Maestro heat-like repeat-containing protein family member 1

1

0

High-throughput

0.513

High

291853

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.513

High

291864

INT2
Integrator complex subunit 2

1

0

High-throughput

0.513

High

291871

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

0

High-throughput

0.513

High

291872

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

High-throughput

0.513

High

291873

PISD
Phosphatidylserine decarboxylase proenzyme, mitochondrial

1

0

High-throughput

0.513

High

291875

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.513

High

291880

NCKP1
Nck-associated protein 1

1

0

High-throughput

0.513

High

291882

DOP1B
Protein DOP1B

1

0

High-throughput

0.513

High

291884

VPP2
V-type proton ATPase 116 kDa subunit a 2

1

0

High-throughput

0.513

High

291751

ELK1
ETS domain-containing protein Elk-1

1

1

Small-scale

0.501

High

291753

CNTF
Ciliary neurotrophic factor

1

0

High-throughput

0.493

High

291778

ICA69
Islet cell autoantigen 1

1

0

High-throughput

0.493

High

291849

EXT2
Exostosin-2

1

0

High-throughput

0.493

High

291801

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

291796

UBE3C
Ubiquitin-protein ligase E3C

1

4

High-throughput

0.489

High

291826

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.489

High

451

NBPFJ
NBPF family member NBPF19

1

11

High-throughput

0.481

High

291766

KR103
Keratin-associated protein 10-3

1

7

High-throughput

0.481

High

291881

KLH20
Kelch-like protein 20

1

7

High-throughput

0.481

High

291741

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.479

High

291773

RSMN
Small nuclear ribonucleoprotein-associated protein N

1

1

High-throughput

0.479

High

291867

MKKS
Molecular chaperone MKKS

1

8

High-throughput

0.479

High

291746

NT2NC
Notch homolog 2 N-terminal-like protein C

1

5

High-throughput

0.470

High

291861

Q9BS75
Kelch-like protein 20

1

7

High-throughput

0.470

High

291802

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.460

High

291806

ZMAT1
Zinc finger matrin-type protein 1

1

4

High-throughput

0.439

High

291842

SRB4D
Scavenger receptor cysteine-rich domain-containing group B protein

1

2

High-throughput

0.439

High

291836

SAXO1
Stabilizer of axonemal microtubules 1

3

0

High-throughput

0.352

High

291843

POF1B
Protein POF1B

2

0

High-throughput

0.328

High

291809

MIIP
Migration and invasion-inhibitory protein

2

0

High-throughput

0.327

High

70057

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

192045

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.316

High

291743

AGR2
Anterior gradient protein 2 homolog

2

0

High-throughput

0.316

High

291823

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

2

0

High-throughput

0.316

High

291838

CCD33
Coiled-coil domain-containing protein 33

2

0

High-throughput

0.310

High

291782

TLE5
TLE family member 5

1

0

High-throughput

0.299

High

291788

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.279

Low

291813

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

291820

SBSN
Suprabasin

1

0

High-throughput

0.279

Low

291817

EBLN2
Endogenous Bornavirus-like nucleoprotein 2

1

0

High-throughput

0.269

Low

291865

Q9HB66
Alternative protein MKKS

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025