HitPredict

Interactor 1: RHBT1 (O94844)
Rho-related BTB domain-containing protein 1
Gene: RHOBTB1

Interactor 2: TPM4 (P67936)
Tropomyosin alpha-4 chain (TM30p1) (Tropomyosin-4)
Gene: TPM4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005856 - cytoskeleton GO:0007015 - actin filament organization
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 696 Hs			1 248
+	Hs
		297568 RHBT1_HUMAN (1-696): 0: 541: 100.00		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		451311 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16
+	Hs
		419042 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		932046 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00
+	Hs
		434429 RHBT2_HUMAN (1-690): 2.28e-168: 502: 67.94		TPM2_HUMAN (4-248): 5.04e-42: 146: 69.39
+	Hs
		451225 CDC42_HUMAN (12-218): 1.55e-89: 279: 37.14		TPM1_HUMAN (4-248): 1.43e-48: 163: 68.16
+	Mm
		823529 CDC42_MOUSE (12-218): 1.55e-89: 279: 37.14		CTRO_MOUSE (4-247): 3.96e-40: 148: 20.65
+	Hs
		925177 RAC1_HUMAN (12-219): 7.28e-73: 235: 35.55		TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00
+	Hs
		418937 RHOG_HUMAN (12-210): 1.67e-69: 226: 36.63		TPM3_HUMAN (4-248): 6.47e-47: 159: 69.39
+	Hs
		931991 RHOG_HUMAN (12-210): 1.67e-69: 226: 36.63		TPM4_HUMAN (1-248): 5.49e-47: 158: 100.00
+	Mm
		823530 RAC1_MOUSE (12-219): 7.28e-73: 235: 35.55		CTRO_MOUSE (4-247): 3.96e-40: 148: 20.65
+	Mm
		823539 RHOA_MOUSE (16-215): 1.65e-68: 224: 36.45		CTRO_MOUSE (4-247): 3.96e-40: 148: 20.65
+	Rn
		92842 RHOA_RAT (16-215): 1.65e-68: 224: 36.45		CTRO_RAT (4-247): 4.34e-39: 146: 20.24