HitPredict

Interactor 1: ERLN2 (O94905)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: ERLIN2

Interactor 2: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 207
+	Hs
		299875 ERLN2_HUMAN (1-339): 5.38e-116: 341: 100.00		RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73
+	Hs
		266127 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		266136 ERLN1_HUMAN (20-333): 1.91e-100: 301: 78.03		RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73
+	Dm
		284092 Q9VWL0_DROME (7-250): 3.46e-67: 216: 18.15		RAB7_DROME (1-207): 1.45e-95: 278: 76.33
+	Dm
		185509 Q9VWL0_DROME (7-250): 3.46e-67: 216: 18.15		O18332_DROME (2-206): 2.18e-83: 247: 32.68
+	Hs
		646145 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		646158 STOM_HUMAN (3-254): 1.4e-70: 223: 16.34		RAB8A_HUMAN (1-205): 1.09e-78: 235: 31.73
+	Hs
		73285 B4E2V5_HUMAN (21-254): 6.78e-62: 199: 16.74		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Hs
		845337 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		RAB7A_HUMAN (1-207): 5.09e-80: 239: 100.00
+	Sc
		701783 PHB1_YEAST (8-249): 3.82e-35: 131: 15.42		YPT7_YEAST (1-207): 3.66e-81: 242: 61.79
+	Hs
		844788 STML2_HUMAN (20-319): 7.67e-59: 195: 14.24		RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44