Protein: ACHA5
Neuronal acetylcholine receptor subunit alpha-5

Gene: ACHA5, CHRNA5
Organism: Homo sapiens
Interactions: 57
UniProt ID: P30532

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0005892 - acetylcholine-gated channel complex
GO:0007165 - signal transduction
GO:0007268 - chemical synaptic transmission
GO:0007271 - synaptic transmission, cholinergic

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

607907

ACHB2
Neuronal acetylcholine receptor subunit beta-2

2

18

Small-scale

0.811

High

720403

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

18

High-throughput

0.691

High

720411

ACHD
Acetylcholine receptor subunit delta

1

18

High-throughput

0.691

High

168382

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.656

High

720432

SIRPD
Signal-regulatory protein delta

1

0

High-throughput

0.656

High

720435

CC50A
Cell cycle control protein 50A

3

0

High-throughput

0.638

High

720421

AGRG5
Adhesion G-protein coupled receptor G5

2

5

High-throughput

0.628

High

698419

CALX
Calnexin

2

7

Small-scale

0.611

High

720415

EREP1
Endosomal transmembrane epsin interactor 1

2

3

High-throughput

0.611

High

720404

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

1

18

Small-scale

0.575

High

516626

LYNX1
Ly-6/neurotoxin-like protein 1

2

6

Small-scale

0.552

High

399434

TRGV3
T cell receptor gamma variable 3

1

0

High-throughput

0.546

High

64344

CDHR4
Cadherin-related family member 4

1

2

High-throughput

0.536

High

65934

LIRA5
Leukocyte immunoglobulin-like receptor subfamily A member 5

1

1

High-throughput

0.536

High

388697

C1QB
Complement C1q subcomponent subunit B

1

6

High-throughput

0.536

High

469777

CATG
Cathepsin G

1

2

High-throughput

0.536

High

720405

WNT3A
Protein Wnt-3a

1

2

High-throughput

0.536

High

720409

IL5RA
Interleukin-5 receptor subunit alpha

1

1

High-throughput

0.536

High

720414

EPHA7
Ephrin type-A receptor 7

1

2

High-throughput

0.536

High

720422

LYPD1
Ly6/PLAUR domain-containing protein 1

1

2

High-throughput

0.536

High

720423

TM87A
Transmembrane protein 87A

1

2

High-throughput

0.536

High

720428

P2RX5
P2X purinoceptor 5

1

4

High-throughput

0.536

High

720430

CNTP3
Contactin-associated protein-like 3

1

1

High-throughput

0.536

High

720434

CBLN4
Cerebellin-4

1

6

High-throughput

0.536

High

720436

P2RX2
P2X purinoceptor 2

1

4

High-throughput

0.536

High

720426

PIEZ1
Piezo-type mechanosensitive ion channel component 1

1

1

High-throughput

0.515

High

231301

EFNA2
Ephrin-A2

1

0

High-throughput

0.513

High

416595

REL1
Prorelaxin H1 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.513

High

506827

CFC1
Cryptic protein

1

0

High-throughput

0.513

High

531981

PPBN
Alkaline phosphatase, germ cell type

1

0

High-throughput

0.513

High

570652

EDN3
Endothelin-3

1

0

High-throughput

0.513

High

596963

TSHR
Thyrotropin receptor

1

0

High-throughput

0.513

High

720413

SLAF1
Signaling lymphocytic activation molecule

1

0

High-throughput

0.513

High

170673

CLGN
Calmegin

1

7

High-throughput

0.489

High

273749

ATS4
A disintegrin and metalloproteinase with thrombospondin motifs 4

1

1

High-throughput

0.489

High

663537

CMA1
Chymase

1

2

High-throughput

0.489

High

720412

SIA4C
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4

1

7

High-throughput

0.489

High

720431

WN10A
Protein Wnt-10a

1

2

High-throughput

0.489

High

217877

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

720420

LYPD6
Ly6/PLAUR domain-containing protein 6

1

6

Small-scale

0.445

High

720424

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

720407

SRPK2
SRSF protein kinase 2

1

0

High-throughput

0.426

High

720406

DEF1
Neutrophil defensin 1

2

0

High-throughput

0.328

High

231036

VEGFD
Vascular endothelial growth factor D

1

0

High-throughput

0.279

Low

327035

NXPH3
Neurexophilin-3

1

0

High-throughput

0.279

Low

342515

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.279

Low

567803

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.279

Low

720408

NDP
Norrin

1

0

High-throughput

0.279

Low

720410

FMOD
Fibromodulin

1

0

High-throughput

0.279

Low

720416

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

720417

DB135
Beta-defensin 135

1

0

High-throughput

0.279

Low

720418

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.279

Low

720419

LYZL1
Lysozyme-like protein 1

1

0

High-throughput

0.279

Low

720425

OIT3
Oncoprotein-induced transcript 3 protein

1

0

High-throughput

0.279

Low

720427

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.279

Low

720429

IL17F
Interleukin-17F

1

0

High-throughput

0.279

Low

720433

KLK15
Kallikrein-15

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025