Protein: AGAL
Alpha-galactosidase A (EC 3.2.1.22) (Alpha-D-galactosidase A) (Alpha-D-galactoside galactohydrolase) (Galactosylgalactosylglucosylceramidase GLA) (Melibiase) (Agalsidase)

Gene: AGAL, GLA
Organism: Homo sapiens
Interactions: 57
UniProt ID: P06280

Gene Ontology (top 5):
GO:0003824 - catalytic activity
GO:0004557 - alpha-galactosidase activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

413082

CALX
Calnexin

3

1

High-throughput

0.650

High

413114

FBX6
F-box only protein 6

2

1

High-throughput

0.584

High

413078

LAMP1
Lysosome-associated membrane glycoprotein 1

2

0

High-throughput

0.547

High

413107

SORT
Sortilin

1

0

Small-scale

0.545

High

177786

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.515

High

254972

DEPD5
GATOR1 complex protein DEPDC5

1

0

High-throughput

0.513

High

354658

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.513

High

413121

G3BP2
Ras GTPase-activating protein-binding protein 2

1

0

High-throughput

0.513

High

413077

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.501

High

411269

INSR
Insulin receptor

1

3

High-throughput

0.500

High

413087

OTUD4
OTU domain-containing protein 4

1

0

High-throughput

0.493

High

204926

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

226263

PRKN
E3 ubiquitin-protein ligase parkin

1

1

High-throughput

0.479

High

413076

MET
Hepatocyte growth factor receptor

1

4

High-throughput

0.479

High

413090

CUL3
Cullin-3

1

3

High-throughput

0.479

High

413095

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.479

High

413100

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.479

High

413110

Q9H4D1
Protein kinase

1

1

High-throughput

0.479

High

153975

TERT
Telomerase reverse transcriptase

1

0

Small-scale

0.460

High

413081

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

413093

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

413101

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.458

High

413102

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

413108

PTN18
Tyrosine-protein phosphatase non-receptor type 18

1

0

High-throughput

0.458

High

413111

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

413116

T106B
Transmembrane protein 106B

1

0

High-throughput

0.458

High

413117

CNOT2
CCR4-NOT transcription complex subunit 2

1

0

High-throughput

0.458

High

413120

CNOT6
CCR4-NOT transcription complex subunit 6

1

0

High-throughput

0.458

High

413075

IGF1R
Insulin-like growth factor 1 receptor

1

3

High-throughput

0.457

High

413088

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

4

High-throughput

0.457

High

413092

NTRK3
NT-3 growth factor receptor

1

2

High-throughput

0.457

High

413084

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

1

High-throughput

0.445

High

413109

ZKSC3
Zinc finger protein with KRAB and SCAN domains 3

1

2

High-throughput

0.445

High

413096

RC3H1
Roquin-1

1

1

Small-scale

0.437

High

413112

RC3H2
Roquin-2

1

1

Small-scale

0.437

High

413115

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.437

High

305899

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

0

High-throughput

0.426

High

413079

MPRI
Cation-independent mannose-6-phosphate receptor

1

0

Small-scale

0.426

High

413086

LRP2
Low-density lipoprotein receptor-related protein 2

1

0

Small-scale

0.426

High

413091

ZNF79
Zinc finger protein 79

1

1

High-throughput

0.407

High

413097

ZFP1
Zinc finger protein 1 homolog

1

1

High-throughput

0.407

High

413104

ZKSC4
Zinc finger protein with KRAB and SCAN domains 4

1

2

High-throughput

0.407

High

413105

ZN764
Zinc finger protein 764

1

3

High-throughput

0.407

High

413106

ZN419
Zinc finger protein 419

1

1

High-throughput

0.407

High

63986

SPDE4
Speedy protein E4

1

0

High-throughput

0.279

Low

413089

NPRL3
GATOR1 complex protein NPRL3

1

0

High-throughput

0.279

Low

413094

ALG11
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase

1

0

High-throughput

0.279

Low

413098

TM205
Transmembrane protein 205

1

0

High-throughput

0.279

Low

413103

NPRL2
GATOR1 complex protein NPRL2

1

0

High-throughput

0.279

Low

413113

RDH14
Retinol dehydrogenase 14

1

0

High-throughput

0.279

Low

174548

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

0

High-throughput

0.261

Low

413080

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

413083

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

413085

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

413099

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

413118

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

0

High-throughput

0.249

Low

413119

CNO11
CCR4-NOT transcription complex subunit 11

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024