Protein: C1QB
Complement C1q subcomponent subunit B

Gene: C1QB
Organism: Homo sapiens
Interactions: 86
UniProt ID: P02746

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005581 - collagen trimer
GO:0005602 - complement component C1 complex
GO:0006956 - complement activation
GO:0006958 - complement activation, classical pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

388594

C1QA
Complement C1q subcomponent subunit A

2

18

Small-scale

0.768

High

388683

FINC
Fibronectin

4

20

Small-scale

0.694

High

388687

CO6A2

1

20

High-throughput

0.691

High

388700

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

20

High-throughput

0.691

High

388735

COCA1

1

20

High-throughput

0.691

High

380241

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

2

High-throughput

0.618

High

388686

CO4A2

1

20

High-throughput

0.618

High

388703

MAP2
Methionine aminopeptidase 2

3

2

High-throughput

0.609

High

388721

UBP30
Ubiquitin carboxyl-terminal hydrolase 30

3

3

High-throughput

0.609

High

388724

P3H3
Prolyl 3-hydroxylase 3

3

20

High-throughput

0.609

High

388701

VHL
von Hippel-Lindau disease tumor suppressor

2

7

High-throughput

0.558

High

388732

SC65
Endoplasmic reticulum protein SC65

2

20

High-throughput

0.558

High

388746

UBQL2
Ubiquilin-2

2

14

High-throughput

0.553

High

388709

TF65
Transcription factor p65

1

2

High-throughput

0.541

High

137021

PLOD2
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

1

20

High-throughput

0.536

High

144034

MA2B1
Lysosomal alpha-mannosidase

1

12

High-throughput

0.536

High

183210

LAMA5
Laminin subunit alpha-5

1

20

High-throughput

0.536

High

323951

CSTN1
Calsyntenin-1

1

10

High-throughput

0.536

High

350672

NOE2
Noelin-2

1

4

High-throughput

0.536

High

388685

BGLR
Beta-glucuronidase

1

5

High-throughput

0.536

High

388688

BMP1
Bone morphogenetic protein 1

1

12

High-throughput

0.536

High

388691

FGFR4
Fibroblast growth factor receptor 4

1

5

High-throughput

0.536

High

388692

FGFR3
Fibroblast growth factor receptor 3

1

5

High-throughput

0.536

High

388693

BDNF
Neurotrophic factor BDNF precursor form

1

1

High-throughput

0.536

High

388696

PCSK6
Proprotein convertase subtilisin/kexin type 6

1

10

High-throughput

0.536

High

388697

ACHA5
Neuronal acetylcholine receptor subunit alpha-5

1

6

High-throughput

0.536

High

388713

GAS6
Growth arrest-specific protein 6

1

18

High-throughput

0.536

High

388720

ARSK
Arylsulfatase K

1

4

High-throughput

0.536

High

388727

VWDE
von Willebrand factor D and EGF domain-containing protein

1

8

High-throughput

0.536

High

388728

PCSK9
Proprotein convertase subtilisin/kexin type 9

1

5

High-throughput

0.536

High

388730

NLGN2
Neuroligin-2

1

4

High-throughput

0.536

High

388734

NAR5
Ecto-ADP-ribosyltransferase 5

1

1

High-throughput

0.536

High

388740

CNTP3
Contactin-associated protein-like 3

1

20

High-throughput

0.536

High

388751

ATS7
A disintegrin and metalloproteinase with thrombospondin motifs 7

1

9

High-throughput

0.536

High

388755

LOXL2
Lysyl oxidase homolog 2

1

5

High-throughput

0.536

High

136583

MANBA
Beta-mannosidase

1

5

High-throughput

0.489

High

388684

INSR
Insulin receptor

1

7

High-throughput

0.489

High

388689

NAGAB
Alpha-N-acetylgalactosaminidase

1

1

High-throughput

0.489

High

388699

CCR1
C-C chemokine receptor type 1

1

2

High-throughput

0.489

High

388702

MA2A2
Alpha-mannosidase 2x

1

12

High-throughput

0.489

High

388704

PLXA3
Plexin-A3

1

10

High-throughput

0.489

High

388706

ANAG
Alpha-N-acetylglucosaminidase

1

1

High-throughput

0.489

High

388711

MGT5A
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

1

1

High-throughput

0.489

High

388716

T132A
Transmembrane protein 132A

1

3

High-throughput

0.489

High

388717

GT253
Inactive glycosyltransferase 25 family member 3

1

20

High-throughput

0.489

High

388719

METRL
Meteorin-like protein

1

6

High-throughput

0.489

High

388723

BMP8A
Bone morphogenetic protein 8A

1

12

High-throughput

0.489

High

388729

CHSTE
Carbohydrate sulfotransferase 14

1

4

High-throughput

0.489

High

388731

PTPRU
Receptor-type tyrosine-protein phosphatase U

1

3

High-throughput

0.489

High

388738

LRFN3
Leucine-rich repeat and fibronectin type-III domain-containing protein 3

1

4

High-throughput

0.489

High

388739

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.489

High

388741

SEM6B
Semaphorin-6B

1

6

High-throughput

0.489

High

388743

CELR1
Cadherin EGF LAG seven-pass G-type receptor 1

1

6

High-throughput

0.489

High

388744

CHPF2
Chondroitin sulfate glucuronyltransferase

1

4

High-throughput

0.489

High

388747

PLXA1
Plexin-A1

1

12

High-throughput

0.489

High

388748

METRN
Meteorin

1

6

High-throughput

0.489

High

388749

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

2

High-throughput

0.489

High

388752

TRHDE
Thyrotropin-releasing hormone-degrading ectoenzyme

1

2

High-throughput

0.489

High

388753

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

2

High-throughput

0.489

High

388754

MA2B2
Epididymis-specific alpha-mannosidase

1

12

High-throughput

0.489

High

388736

MYOC
Myocilin

1

4

Small-scale

0.481

High

388695

PTX3
Pentraxin-related protein PTX3

1

5

Small-scale

0.479

High

388715

RAGE
Advanced glycosylation end product-specific receptor

1

6

Small-scale

0.479

High

388722

CF120
UPF0669 protein C6orf120

1

0

High-throughput

0.458

High

271804

OBSL1
Obscurin-like protein 1

1

6

High-throughput

0.437

High

277241

PITX3
Pituitary homeobox 3

1

2

Small-scale

0.437

High

285025

EED
Polycomb protein EED

1

1

High-throughput

0.437

High

388690

EGR1
Early growth response protein 1

1

2

High-throughput

0.437

High

388707

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.437

High

388714

TNIP1
TNFAIP3-interacting protein 1

1

4

High-throughput

0.437

High

388726

GT252
Procollagen galactosyltransferase 2

1

20

High-throughput

0.437

High

388733

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.437

High

388710

DMWD
Dystrophia myotonica WD repeat-containing protein

2

0

High-throughput

0.328

High

388705

AT12A
Potassium-transporting ATPase alpha chain 2

2

0

High-throughput

0.318

High

388742

TNR27
Tumor necrosis factor receptor superfamily member 27

1

0

High-throughput

0.282

High

287844

MYCB2
E3 ubiquitin-protein ligase MYCBP2

1

0

High-throughput

0.279

Low

388708

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

0

High-throughput

0.279

Low

388712

HYAL2
Hyaluronidase-2

1

0

High-throughput

0.279

Low

388718

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

0

High-throughput

0.279

Low

388725

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

1

0

High-throughput

0.279

Low

388737

ZNG1A
Zinc-regulated GTPase metalloprotein activator 1A

1

0

High-throughput

0.279

Low

388750

NOCT
Nocturnin

1

0

High-throughput

0.279

Low

388694

IL32
Interleukin-32

1

0

Small-scale

0.251

Low

319276

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.249

Low

388698

GLPK
Glycerol kinase

1

0

High-throughput

0.249

Low

388745

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025