HitPredict

Interactor 1: PRP6 (O94906)
Pre-mRNA-processing factor 6 (Androgen receptor N-terminal domain-transactivating protein 1) (ANT-1) (PRP6 homolog) (U5 snRNP-associated 102 kDa protein) (U5-102 kDa protein)
Gene: PRPF6

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0008380 - RNA splicing
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 941 Hs			1 582
+	Hs
		300187 PRP6_HUMAN (1-941): 0: 610: 100.00		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Hs
		1057942 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Hs
		1116329 CTR9_HUMAN (126-536): 3.3e-16: 85.7: 10.12		LARP7_HUMAN (1-582): 1.26e-127: 388: 100.00
+	Sc
		376625 PRP6_YEAST (4-924): 7.58e-80: 280: 21.50		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		1058025 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		1174813 PRP39_HUMAN (425-927): 1.16e-23: 109: 15.92		LARP4_HUMAN (22-216): 3.23e-40: 157: 21.32
+	Mm
		665754 CTR9_MOUSE (126-536): 5.01e-16: 85.3: 10.12		PABP1_MOUSE (1-405): 3.35e-40: 156: 10.05
+	Hs
		174546 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		1058049 RRP5_HUMAN (474-761): 1.34e-26: 120: 14.09		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Hs
		174849 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		PABP4_HUMAN (1-208): 8.15e-41: 158: 11.98
+	Hs
		174583 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Sc
		376611 CYC8_YEAST (641-915): 1.29e-13: 77.2: 17.12		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		175076 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		LAR4B_HUMAN (2-216): 8.48e-36: 145: 17.02
+	Sc
		376930 RRP5_YEAST (276-524): 4.45e-12: 72.5: 17.28		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		1288635 SYF1_HUMAN (109-527): 1.77e-12: 73.4: 13.78		PABP5_HUMAN (12-206): 7.64e-32: 128: 14.15
+	Hs
		174975 OGT1_HUMAN (120-352): 4.99e-10: 65.7: 11.39		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23