HitPredict - High confidence protein-protein interactions

Interactor 1: HEXI1 (O94992)
Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1)
Gene: HEXIM1

Interactor 2: HEXI1 (O94992)
Protein HEXIM1 (Cardiac lineage protein 1) (Estrogen down-regulated gene 1 protein) (Hexamethylene bis-acetamide-inducible protein 1) (Menage a quatre protein 1)
Gene: HEXIM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	1.00	0.835

Property	Details
Experiments	15855166, 17724342, 31515488
Identification Methods	pull down, nuclear magnetic resonance, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	HEXIM~HEXIM
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0002218 - activation of innate immune response GO:0004860 - protein kinase inhibitor activity GO:0004861 - cyclin-dependent protein serine/threonine kinase inhibitor activity GO:0005634 - nucleus and 14 others more... GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0007507 - heart development GO:0017069 - snRNA binding GO:0032897 - negative regulation of viral transcription GO:0034244 - negative regulation of transcription elongation by RNA polymerase II GO:0043231 - intracellular membrane-bounded organelle GO:0045087 - innate immune response GO:0045736 - negative regulation of cyclin-dependent protein serine/threonine kinase activity GO:0045892 - negative regulation of DNA-templated transcription GO:0097322 - 7SK snRNA binding GO:0106140 - P-TEFb complex binding GO:0120259 - 7SK snRNP GO:1901798 - positive regulation of signal transduction by p53 class mediator
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1	359
Hs

1	359

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Last updated: 15 Jul 2024