HitPredict

Interactor 1: O76354 (O76354)
RING-type domain-containing protein
Gene: C45G7.4

Interactor 2: UBC2 (P35129)
Ubiquitin-conjugating enzyme E2 2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 2) (Lethal protein 70) (Ubiquitin carrier protein 2) (Ubiquitin-protein ligase 2)
Gene: let-70

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	15530417
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_UBOX
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 603 Ce			1 147
+	Hs
		1420598 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UB2D4_HUMAN (1-147): 1e-83: 243: 92.52
+	Hs
		906777 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12
+	Hs
		982314 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UB2D2_HUMAN (1-147): 2.1e-82: 240: 93.88
+	Hs
		957193 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UB2D3_HUMAN (1-147): 3.15e-81: 237: 92.52
+	Hs
		1397292 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UB2E2_HUMAN (4-146): 1.75e-74: 222: 66.43
+	Hs
		1381200 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UB2E3_HUMAN (4-146): 7.58e-74: 221: 66.43
+	Hs
		783461 TRI23_HUMAN (20-273): 4.57e-44: 167: 17.56		UB2D4_HUMAN (1-147): 1e-83: 243: 92.52
+	Hs
		909387 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UB2E1_HUMAN (4-146): 2.39e-72: 216: 66.43
+	Hs
		783205 TRI23_HUMAN (20-273): 4.57e-44: 167: 17.56		UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12
+	Hs
		783223 TRI23_HUMAN (20-273): 4.57e-44: 167: 17.56		UB2D2_HUMAN (1-147): 2.1e-82: 240: 93.88
+	Hs
		906818 TRIM1_HUMAN (4-269): 6.62e-43: 166: 18.02		UB2D1_HUMAN (1-147): 7.56e-83: 241: 89.12
+	Hs
		982356 TRIM1_HUMAN (4-269): 6.62e-43: 166: 18.02		UB2D2_HUMAN (1-147): 2.1e-82: 240: 93.88
+	Hs
		783212 TRI23_HUMAN (20-273): 4.57e-44: 167: 17.56		UB2D3_HUMAN (1-147): 3.15e-81: 237: 92.52
+	Hs
		957232 TRIM1_HUMAN (4-269): 6.62e-43: 166: 18.02		UB2D3_HUMAN (1-147): 3.15e-81: 237: 92.52
+	Hs
		957838 TRIM2_HUMAN (6-277): 1.25e-52: 194: 18.53		UBE2N_HUMAN (4-147): 7.35e-69: 206: 47.22
+	Hs
		783375 TRI23_HUMAN (20-273): 4.57e-44: 167: 17.56		UB2E2_HUMAN (4-146): 1.75e-74: 222: 66.43
+	Hs
		783206 TRI23_HUMAN (20-273): 4.57e-44: 167: 17.56		UB2E1_HUMAN (4-146): 2.39e-72: 216: 66.43
+	Hs
		909409 TRIM1_HUMAN (4-269): 6.62e-43: 166: 18.02		UB2E1_HUMAN (4-146): 2.39e-72: 216: 66.43
+	Hs
		783213 TRI23_HUMAN (20-273): 4.57e-44: 167: 17.56		UBE2N_HUMAN (4-147): 7.35e-69: 206: 47.22
+	Hs
		957862 TRIM1_HUMAN (4-269): 6.62e-43: 166: 18.02		UBE2N_HUMAN (4-147): 7.35e-69: 206: 47.22