Protein: TRIM2
Tripartite motif-containing protein 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM2) (RING finger protein 86) (RING-type E3 ubiquitin transferase TRIM2)

Gene: TRIM2
Organism: Homo sapiens
Interactions: 53
UniProt ID: Q9C040

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0004842 - ubiquitin-protein transferase activity
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

279069

TRIM3
Tripartite motif-containing protein 3

5

17

Small-scale

0.924

High

906777

UB2D1
Ubiquitin-conjugating enzyme E2 D1

3

20

Small-scale

0.868

High

909387

UB2E1
Ubiquitin-conjugating enzyme E2 E1

2

20

Small-scale

0.800

High

957193

UB2D3
Ubiquitin-conjugating enzyme E2 D3

2

20

Small-scale

0.800

High

982314

UB2D2
Ubiquitin-conjugating enzyme E2 D2

2

20

Small-scale

0.800

High

1383933

UBE2W
Ubiquitin-conjugating enzyme E2 W

2

20

Small-scale

0.800

High

1397292

UB2E2
Ubiquitin-conjugating enzyme E2 E2

2

20

Small-scale

0.800

High

1420598

UB2D4
Ubiquitin-conjugating enzyme E2 D4

2

20

Small-scale

0.800

High

957665

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

High-throughput

0.783

High

971047

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

20

High-throughput

0.698

High

1218761

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

20

High-throughput

0.698

High

1381200

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

High-throughput

0.698

High

1420180

TRIM8
E3 ubiquitin-protein ligase TRIM8

1

19

High-throughput

0.698

High

1237963

LRC8E
Volume-regulated anion channel subunit LRRC8E

4

4

High-throughput

0.697

High

1420595

TRIM2
Tripartite motif-containing protein 2

1

15

Small-scale

0.692

High

144193

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

Small-scale

0.647

High

957838

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

20

Small-scale

0.647

High

970226

UB2G1
Ubiquitin-conjugating enzyme E2 G1

1

20

Small-scale

0.647

High

1412783

UBAC1
Ubiquitin-associated domain-containing protein 1

4

9

High-throughput

0.642

High

1420596

NUFP1
FMR1-interacting protein NUFIP1

3

0

High-throughput

0.638

High

1255431

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1400581

CIB3
Calcium and integrin-binding family member 3

3

4

High-throughput

0.616

High

1398286

KCTD7
BTB/POZ domain-containing protein KCTD7

2

11

High-throughput

0.606

High

1005374

SHPS1
Tyrosine-protein phosphatase non-receptor type substrate 1

3

7

High-throughput

0.599

High

1420597

TNIK
TRAF2 and NCK-interacting protein kinase

2

14

High-throughput

0.590

High

1380510

UBE2F
NEDD8-conjugating enzyme UBE2F

1

20

Small-scale

0.579

High

908783

MAT1
CDK-activating kinase assembly factor MAT1

1

4

High-throughput

0.541

High

530344

TAU
Microtubule-associated protein tau

1

15

High-throughput

0.536

High

1115990

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

13

High-throughput

0.536

High

1399933

KLHL5
Kelch-like protein 5

1

7

High-throughput

0.536

High

106608

APRIO
Alternative prion protein

2

4

High-throughput

0.533

High

75533

B3KSH4
Huntingtin interacting protein 2, isoform CRA_a

1

20

High-throughput

0.528

High

846466

MATR3
Matrin-3

1

10

High-throughput

0.515

High

335263

CXB5
Gap junction beta-5 protein

1

6

High-throughput

0.494

High

1316628

CDK20
Cyclin-dependent kinase 20

1

8

High-throughput

0.494

High

639307

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

11

High-throughput

0.481

High

885889

KC1E
Casein kinase I isoform epsilon

1

8

High-throughput

0.481

High

1389796

DTBP1
Dysbindin

1

5

High-throughput

0.481

High

350133

SNAI1
Zinc finger protein SNAI1

1

20

Small-scale

0.479

High

414567

P53
Cellular tumor antigen p53

1

17

Small-scale

0.479

High

461905

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.479

High

468774

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

1114231

CUL3
Cullin-3

1

16

High-throughput

0.479

High

510021

HMN1
Humanin-like 1

1

0

Small-scale

0.458

High

219657

B2L11
Bcl-2-like protein 11

1

2

Small-scale

0.457

High

1056954

FMR1
Fragile X messenger ribonucleoprotein 1

1

8

High-throughput

0.457

High

935102

TERA
Transitional endoplasmic reticulum ATPase

1

8

High-throughput

0.445

High

1387335

OTUB2
Ubiquitin thioesterase OTUB2

1

11

High-throughput

0.439

High

1291356

LCA5
Lebercilin

1

14

High-throughput

0.437

High

404900

PRIO
Major prion protein

1

0

High-throughput

0.426

High

1394744

COG3
Conserved oligomeric Golgi complex subunit 3

2

0

High-throughput

0.316

High

276858

VATG1
V-type proton ATPase subunit G 1

1

0

High-throughput

0.269

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025