HitPredict

Interactor 1: UBR5 (O95071)
E3 ubiquitin-protein ligase UBR5 (EC 2.3.2.26) (E3 ubiquitin-protein ligase, HECT domain-containing 1) (HECT-type E3 ubiquitin transferase UBR5) (Hyperplastic discs protein homolog) (hHYD) (Progestin-induced protein)
Gene: UBR5

Interactor 2: MYL6 (P60660)
Myosin light polypeptide 6 (17 kDa myosin light chain) (LC17) (Myosin light chain 3) (MLC-3) (Myosin light chain alkali 3) (Myosin light chain A3) (Smooth muscle and nonmuscle myosin light chain alkali 6)
Gene: MYL6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	33777788
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2799 Hs			1 151
+	Hs
		125293 WWP2_HUMAN (2430-2797): 2.93e-130: 435: 20.94		MYL6_HUMAN (1-151): 9.61e-42: 137: 100.00
+	Hs
		648627 HECW2_HUMAN (2170-2798): 1.03e-139: 482: 19.72		CALL3_HUMAN (5-77): 1.25e-10: 57.9: 26.03
+	Hs
		538682 HUWE1_HUMAN (2499-2798): 1.29e-100: 366: 27.27		MYL6B_HUMAN (3-150): 2.63e-42: 141: 81.76
+	Hs
		483932 UBE3C_HUMAN (2301-2796): 5.2e-128: 435: 20.33		CALM1_HUMAN (5-77): 1.13e-11: 60.6: 28.77
+	Hs
		484006 UBE3C_HUMAN (2301-2796): 5.2e-128: 435: 20.33		CALM2_HUMAN (5-77): 1.13e-11: 60.6: 28.77
+	Hs
		484130 UBE3C_HUMAN (2301-2796): 5.2e-128: 435: 20.33		CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77
+	Hs
		484077 NEDD4_HUMAN (2446-2796): 8.62e-120: 416: 23.98		CALM3_HUMAN (5-77): 1.13e-11: 60.6: 28.77