HitPredict

Interactor 1: O77430 (O77430)
GEO01111p1 (HL01263p) (RH26825p) (SKP1-related A, isoform A) (SKP1-related A, isoform B) (SKP1-related A, isoform C) (SKP1-related A, isoform E) (SKP1-related A, isoform F) (SKP1-related A, isoform G) (SKPA)
Gene: SkpA

Interactor 2: Q8T4E7 (Q8T4E7)
AT02038p (AT13284p)
Gene: DmelCG13088

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 162 Dm			1 401
+	Hs
		992385 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FBXL2_HUMAN (3-383): 2.53e-76: 244: 13.82
+	Mm
		1423931 SKP1_MOUSE (1-162): 2.53e-84: 246: 76.07		FXL20_MOUSE (3-383): 1.06e-69: 227: 13.53
+	Dm
		305522 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q9VMA6_DROME (1-365): 4.12e-70: 228: 27.27
+	Hs
		992302 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FXL20_HUMAN (3-383): 6.56e-70: 228: 13.53
+	Dm
		305546 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q9W214_DROME (1-355): 1.46e-64: 216: 17.59
+	Ce
		111130 SKR1_CAEEL (4-161): 5.82e-79: 233: 63.35		FBXL_CAEEL (4-383): 8.4e-67: 221: 14.11
+	Dm
		305526 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q9VNX7_DROME (1-381): 8.39e-59: 199: 19.05
+	Dm
		305517 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q9VKF2_DROME (1-332): 5.6e-57: 194: 23.40
+	Dm
		305506 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q9VED4_DROME (1-352): 1.62e-55: 191: 15.82
+	Dm
		305515 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q9VIK3_DROME (1-337): 1.62e-50: 177: 17.25
+	Dm
		305484 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q8T437_DROME (1-337): 3.41e-50: 176: 17.52
+	Hs
		992358 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FXL12_HUMAN (1-331): 2.77e-43: 155: 17.26
+	Ce
		111144 SKR1_CAEEL (4-161): 5.82e-79: 233: 63.35		Q8MQ34_CAEEL (4-326): 1.4e-41: 153: 13.29
+	Hs
		992251 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FXL14_HUMAN (47-285): 3.86e-24: 105: 14.51
+	Hs
		992373 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FBXL7_HUMAN (27-271): 3.94e-22: 99.8: 14.12
+	Hs
		992383 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FBXL4_HUMAN (162-356): 1.79e-17: 86.3: 16.43
+	Hs
		992366 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FXL17_HUMAN (222-365): 1.17e-10: 65.1: 10.27
+	Dm
		305507 O77430_DROME (1-162): 1.06e-83: 245: 100.00		Q9VF10_DROME (154-360): 4.76e-10: 63.6: 12.50
+	Hs
		992330 SKP1_HUMAN (1-162): 4.57e-84: 245: 76.69		FXL15_HUMAN (6-247): 1.19e-09: 60.9: 19.07
+	Mm
		1490138 SKP1_MOUSE (1-162): 2.53e-84: 246: 76.07		SKP2_MOUSE (2-255): 4.87e-09: 59.8: 16.49