HitPredict

Interactor 1: ZFYV9 (O95405)
Zinc finger FYVE domain-containing protein 9 (Mothers against decapentaplegic homolog-interacting protein) (Madh-interacting protein) (Novel serine protease) (NSP) (Receptor activation anchor) (hSARA) (Smad anchor for receptor activation)
Gene: ZFYVE9

Interactor 2: ANFY1 (Q9P2R3)
Rabankyrin-5 (Rank-5) (Ankyrin repeat and FYVE domain-containing protein 1) (Ankyrin repeats hooked to a zinc finger motif)
Gene: ANKFY1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE~FYVE
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol GO:0006897 - endocytosis GO:0016197 - endosomal transport GO:0043231 - intracellular membrane-bounded organelle and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1425 Hs			1 1169
+	Hs
		1189523 ZFY16_HUMAN (1-1424): 0: 1145: 30.54		ANFY1_HUMAN (1-1169): 0: 717: 100.00
+	Hs
		1302778 RUFY1_HUMAN (156-763): 1.92e-101: 342: 14.72		ANFY1_HUMAN (1-1169): 0: 717: 100.00
+	Hs
		1067481 EEA1_HUMAN (2-758): 9.63e-69: 257: 12.42		ANFY1_HUMAN (1-1169): 0: 717: 100.00
+	Hs
		1237559 ANFY1_HUMAN (222-758): 6.51e-50: 196: 12.77		ANR44_HUMAN (2-903): 1.58e-118: 393: 18.51
+	Hs
		166924 MTMR3_HUMAN (196-777): 2.87e-71: 263: 13.18		ANR28_HUMAN (871-1156): 6.5e-49: 191: 19.86
+	Hs
		92407 E9PDH4_HUMAN (570-895): 1.04e-41: 170: 15.25		ANK1_HUMAN (1-533): 2.33e-63: 239: 17.07
+	Hs
		556723 FYV1_HUMAN (570-895): 6.39e-41: 168: 15.25		ANK1_HUMAN (1-533): 2.33e-63: 239: 17.07
+	Hs
		167028 ANFY1_HUMAN (222-758): 6.51e-50: 196: 12.77		ANR28_HUMAN (871-1156): 6.5e-49: 191: 19.86
+	Mm
		57422 EEA1_MOUSE (2-758): 7.05e-62: 235: 12.40		A2AM57_MOUSE (4-358): 3.62e-20: 99.2: 13.76