HitPredict

Interactor 1: A0A0S2Z4D7 (A0A0S2Z4D7)
NCK adaptor protein 1 isoform 2 (NCK adaptor protein 1, isoform CRA_b)
Gene: NCK1

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	26871637
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH3_1~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 170 Hs			1 513
+	Hs
		442853 HCK_HUMAN (2-169): 1.03e-52: 176: 21.59		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		433885 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		411788 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		454841 FGR_HUMAN (6-166): 2.81e-47: 162: 19.41		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		412258 FYN_HUMAN (6-160): 4.63e-46: 159: 20.73		ABI1_HUMAN (1-513): 3.84e-97: 304: 61.00
+	Hs
		442894 HCK_HUMAN (2-169): 1.03e-52: 176: 21.59		ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66
+	Mm
		639446 LYN_MOUSE (2-169): 7.16e-52: 174: 18.75		SRC8_MOUSE (272-507): 8.45e-33: 133: 17.80
+	Hs
		203198 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92
+	Mm
		639438 LYN_MOUSE (2-169): 7.16e-52: 174: 18.75		HCLS1_MOUSE (271-508): 2.64e-32: 131: 21.30
+	Hs
		433732 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		MYO1E_HUMAN (325-508): 7.96e-32: 132: 22.68
+	Hs
		411580 LCK_HUMAN (3-169): 3.75e-50: 169: 19.43		VAV_HUMAN (276-513): 8.6e-32: 131: 17.86
+	Mm
		411921 LCK_MOUSE (3-169): 2.41e-49: 167: 19.43		HCLS1_MOUSE (271-508): 2.64e-32: 131: 21.30
+	Hs
		433551 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		HCLS1_HUMAN (271-508): 6.94e-30: 124: 19.86
+	Hs
		297808 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		K0754_HUMAN (111-451): 1.58e-28: 122: 16.09
+	Hs
		411981 FYN_HUMAN (6-160): 4.63e-46: 159: 20.73		VAV_HUMAN (276-513): 8.6e-32: 131: 17.86
+	Mm
		763381 FYN_MOUSE (6-160): 4.58e-46: 159: 20.73		HCLS1_MOUSE (271-508): 2.64e-32: 131: 21.30
+	Hs
		454795 FGR_HUMAN (6-166): 2.81e-47: 162: 19.41		HCLS1_HUMAN (271-508): 6.94e-30: 124: 19.86
+	Mm
		639449 LYN_MOUSE (2-169): 7.16e-52: 174: 18.75		DBNL_MOUSE (293-508): 1.64e-17: 87: 22.07
+	Mm
		763393 FYN_MOUSE (6-160): 4.58e-46: 159: 20.73		GRB2_MOUSE (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		433781 LYN_HUMAN (2-169): 2.46e-51: 172: 18.75		ITSN1_HUMAN (380-510): 4.82e-12: 71: 15.22