HitPredict

Interactor 1: PCNT (O95613)
Pericentrin (Kendrin) (Pericentrin-B)
Gene: PCNT

Interactor 2: SYNE1 (Q8NF91)
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)
Gene: SYNE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	35914814
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3336 Hs			1 8797
+	Hs
		164543 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12
+	Hs
		317231 PCNT_HUMAN (1-3336): 0: 718: 100.00		DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83
+	Hs
		317252 PCNT_HUMAN (1-3336): 0: 718: 100.00		PLEC_HUMAN (7019-8757): 8.37e-37: 158: 9.89
+	Hs
		317230 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49
+	Hs
		317377 PCNT_HUMAN (1-3336): 0: 718: 100.00		MACF1_HUMAN (7352-8757): 1.08e-27: 128: 11.64
+	Hs
		317246 PCNT_HUMAN (1-3336): 0: 718: 100.00		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Hs
		317220 PCNT_HUMAN (1-3336): 0: 718: 100.00		UTRN_HUMAN (7111-8757): 2.11e-24: 117: 11.28
+	Hs
		317286 PCNT_HUMAN (1-3336): 0: 718: 100.00		SYNE3_HUMAN (3282-3947): 9.91e-14: 81.3: 19.39
+	Hs
		974137 CP250_HUMAN (1630-3336): 3.41e-53: 210: 10.43		DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83
+	Hs
		969584 CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Dm
		1182584 LVA_DROME (1967-3211): 1.36e-32: 142: 10.43		Q7KV70_DROME (3665-7077): 4.44e-48: 195: 10.43
+	Hs
		969597 CENPE_HUMAN (1328-3305): 2.89e-65: 250: 10.28		SYNE3_HUMAN (3282-3947): 9.91e-14: 81.3: 19.39
+	Hs
		166696 CE290_HUMAN (1764-3201): 5.48e-34: 147: 10.55		DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83
+	Mm
		513821 PLEC_MOUSE (2-1335): 1.57e-39: 165: 10.63		DMD_MOUSE (7119-8762): 3.85e-28: 129: 10.98
+	Hs
		164575 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		SPTN2_HUMAN (18-355): 7.94e-49: 197: 39.12
+	Hs
		110636 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		H3BPE1_HUMAN (15-1509): 2.18e-44: 183: 14.24
+	Hs
		724786 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		DYST_HUMAN (12-1547): 1.58e-42: 177: 13.83
+	Hs
		1061289 NUMA1_HUMAN (43-1227): 1.53e-33: 145: 10.92		MACF1_HUMAN (7352-8757): 1.08e-27: 128: 11.64
+	Hs
		522612 MYH7_HUMAN (2483-3316): 1.1e-33: 146: 12.07		SPTN1_HUMAN (7955-8728): 7.08e-25: 118: 13.61
+	Hs
		724781 MYH9_HUMAN (2690-3313): 1.18e-18: 96.7: 9.89		SPTB2_HUMAN (4116-5904): 9.82e-28: 128: 9.49