HitPredict

Interactor 1: DIRA3 (O95661)
GTP-binding protein Di-Ras3 (Distinct subgroup of the Ras family member 3) (Rho-related GTP-binding protein RhoI)
Gene: DIRAS3

Interactor 2: SPTB2 (Q01082)
Spectrin beta chain, non-erythrocytic 1 (Beta-II spectrin) (Fodrin beta chain) (Spectrin, non-erythroid beta chain 1)
Gene: SPTBN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 229 Hs			1 2364
+	Hs
		914014 RB11A_HUMAN (33-227): 1.96e-77: 233: 23.33		SPTB2_HUMAN (1-2364): 0: 751: 100.00
+	Dm
		574833 RHEB_DROME (36-196): 5.52e-22: 90.9: 32.72		ACTN_DROME (48-775): 2.3e-98: 342: 32.43
+	Hs
		297804 DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00		K0754_HUMAN (210-1343): 2.52e-36: 154: 15.07
+	Hs
		318112 DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		318130 DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89
+	Hs
		914020 RB11A_HUMAN (33-227): 1.96e-77: 233: 23.33		DYST_HUMAN (537-1421): 8.42e-22: 106: 12.00
+	Hs
		164544 DIRA3_HUMAN (1-229): 8.18e-88: 260: 100.00		SPTN2_HUMAN (1661-2338): 1.76e-11: 72.4: 15.10
+	Hs
		914061 RB11A_HUMAN (33-227): 1.96e-77: 233: 23.33		SPTN1_HUMAN (152-1087): 9.93e-19: 96.3: 16.89